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Determining Core Capabilities in Chemical and Biological Defense Science and Technology

Determining Core Capabilities in Chemical and Biological Defense Science and Technology
Author: National Research Council
Publisher: National Academies Press
Total Pages: 141
Release: 2013-01-13
Genre: Technology & Engineering
ISBN: 0309265355

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The goal of the U.S. Department of Defense's (DoD's) Chemical and Biological Defense Program (CBDP) is to provide support and world-class capabilities enabling he U.S. Armed Forces to fight and win decisively in chemical, biological, radiological, and nuclear (CBRN) environments. To accomplish this objective, the CBDP must maintain robust science and technology capabilities to support the research, development, testing, and evaluation required for the creation and validation of the products the program supplies. The threat from chemical and biological attack evolves due to the changing nature of conflict and rapid advances in science and technology (S&T), so the core S&T capabilities that must be maintained by the CBDP must also continue to evolve. In order to address the challenges facing the DoD, the Deputy Assistant Secretary of Defense (DASD) for Chemical and Biological Defense (CBD) asked the National Research Council (NRC) to conduct a study to identify the core capabilities in S&T that must be supported by the program. The NRC Committee on Determining Core Capabilities in Chemical and Biological Defense Research and Development examined the capabilities necessary for the chemical and biological defense S&T program in the context of the threat and of the program's stated mission and priorities. Determining Core Capabilities in Chemical and Biological Defense Science and Technology contains the committee's findings and recommendations. It is intended to assist the DASD CBD in determining the best strategy for acquiring, developing, and/or maintaining the needed capabilities.


Chemical and Biological Defense

Chemical and Biological Defense
Author: United States. General Accounting Office
Publisher:
Total Pages: 16
Release: 1993
Genre: Biological weapons
ISBN:

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Industrialization of Biology

Industrialization of Biology
Author: National Research Council
Publisher: National Academies Press
Total Pages: 158
Release: 2015-06-29
Genre: Science
ISBN: 0309316553

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The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.


Spills of Diluted Bitumen from Pipelines

Spills of Diluted Bitumen from Pipelines
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 167
Release: 2016-03-22
Genre: Nature
ISBN: 0309380103

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Diluted bitumen has been transported by pipeline in the United States for more than 40 years, with the amount increasing recently as a result of improved extraction technologies and resulting increases in production and exportation of Canadian diluted bitumen. The increased importation of Canadian diluted bitumen to the United States has strained the existing pipeline capacity and contributed to the expansion of pipeline mileage over the past 5 years. Although rising North American crude oil production has resulted in greater transport of crude oil by rail or tanker, oil pipelines continue to deliver the vast majority of crude oil supplies to U.S. refineries. Spills of Diluted Bitumen from Pipelines examines the current state of knowledge and identifies the relevant properties and characteristics of the transport, fate, and effects of diluted bitumen and commonly transported crude oils when spilled in the environment. This report assesses whether the differences between properties of diluted bitumen and those of other commonly transported crude oils warrant modifications to the regulations governing spill response plans and cleanup. Given the nature of pipeline operations, response planning, and the oil industry, the recommendations outlined in this study are broadly applicable to other modes of transportation as well.


Nuclear Proliferation and Terrorism in the Post-9/11 World

Nuclear Proliferation and Terrorism in the Post-9/11 World
Author: David Hafemeister
Publisher: Springer
Total Pages: 446
Release: 2016-03-29
Genre: Science
ISBN: 3319253670

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This book fills a clear gap in the literature for a technically-focused book covering nuclear proliferation and related issues post-9/11. Using a concept-led approach which serves a broad readership, it provides detailed overview of nuclear weapons, nuclear proliferation and international nuclear policy. The author addresses topics including offensive and defensive missile systems, command and control, verification, weapon effects, and nuclear testing. A chronology of nuclear arms is presented including detailed discussion of the Cold War, proliferation, and arms control treaties. The book is tailored to courses on nuclear proliferation, and the general reader will also find it a fascinating introduction to the science and strategy behind international nuclear policy in the modern era.


National Security and Homeland Defense

National Security and Homeland Defense
Author: National Research Council
Publisher: National Academies Press
Total Pages: 122
Release: 2002-12-04
Genre: Technology & Engineering
ISBN: 0309085047

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This is the first report of seven in the Challenges for the Chemical Sciences in the 21st Century series. The report is based on discussions and presentations at a workshop, and is intended to help scientists and funding agencies set short- and long-term research agendas. It focuses on the challenges for chemists and chemical engineers with respect to threat reduction, preparation, situational awareness, and threat neutralization and remediation


Chemical and Biological Defense

Chemical and Biological Defense
Author: U S Government Accountability Office (G
Publisher: BiblioGov
Total Pages: 32
Release: 2013-06
Genre:
ISBN: 9781289133757

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Pursuant to a congressional request, GAO examined the extent to which the Department of Defense (DOD) has applied the Government Performance and Results Act's outcome-oriented principles to the Chemical and Biological (CB) Defense Program, focusing on whether: (1) CB Defense Program goals are explicit and measurable; (2) the CB Defense Program has performance measures that assess outcomes and impacts rather than outputs and activities; and (3) organizations executing the CB Defense research, development, testing, and evaluation (RDT&E) activities have incorporated Results Act principles in their program planning and evaluation. GAO noted that: (1) DOD's CB Defense Program in general, and its RDT&E activities in particular, have not incorporated key Results Act principles, as evidenced by the fact that the goals of the program are vague and unmeasurable and do not articulate specific desired impacts; (2) in the absence of explicit and measurable goals, it is difficult to assess whether the program has been successful in achieving its goals; (3) the performance measures of CB Defense Program RDT&E emphasize activities rather than impacts; (4) the program is not being evaluated according to its impact on the defensive or operational capabilities of U.S. forces, either individually or collectively; (5) CB Defense Program planners use roadmaps to track program progress toward meeting chemical and biological defense goals; (6) these goals frequently take the form of advanced concept technology demonstrations; (7) however, the demonstration of a new defensive technology or capability is not a measure of the program's impact or contribution to the military's ability to survive, fight, and win in chemical and biological environments; (8) CB Defense Program research and development organizations have incorporated Results Act principles inconsistently; (9) only one organization had adopted the Results Act planning and evaluation tools; and (10) the remaining research and development organizations cited either the utilization of equivalent planning tools or the unique challenges of evaluating research and development activities as reasons why they had not or could not adopt the Results Act processes.


Early Observations on Possible Defenses by the Emerging Threat Agent Project

Early Observations on Possible Defenses by the Emerging Threat Agent Project
Author: Bruce W. Bennett
Publisher: Rand Corporation
Total Pages: 44
Release: 2011
Genre: History
ISBN: 0833052810

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The Defense Department's 2010 Quadrennial Defense Review expressed concerns about emerging chemical and biological (CB) weapon agents and the ability of U.S. defenses to counter them. Scientific advances that facilitate the development of new and novel CB agents and the difficulties uncovering such work suggest that adversary programs could acquire new CB agents years before U.S. defense planners recognize those agents. Once these CB agents are recognized as threats, the United States will probably need many more years to establish a comprehensive defense against them, and even these defenses are unlikely to protect the civilians, contractors, and allied military personnel essential to modern U.S. military operations. Such gaps in CB agent defense capabilities pose a potentially serious risk to U.S. military operations. To best mitigate this risk, the U.S. Chemical and Biological Defense Program (CBDP) needs to augment current work with enhanced efforts to dissuade adversary CB agent development and to deter adversary use of new CB weapons. Successful initiatives in dissuasion and deterrence will depend on CB defensive programs that appear dynamic, progressive, and integrated with other Defense Department and national-level efforts in counterproliferation. The CBDP could add a second track to the current agent-specific science and technology effort to focus on the mechanisms of CB agent effects and interactions with the environment. The goal of the resulting robust combination of CBDP defense, dissuasion, and deterrence is to induce great doubts in adversaries about the value of employing any CB agents or developing new CB agents.


Chemical and Biological Defense Test and Evaluation (T&E) Future Challenges

Chemical and Biological Defense Test and Evaluation (T&E) Future Challenges
Author: James J. Valdes
Publisher:
Total Pages: 10
Release: 2012
Genre: Military research
ISBN:

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The objective of this study was to identify emerging technical, methodological, and infrastructure challenges for future Chemical and Biological Defense (CBD) Test and Evaluation (T&E) investment, and to serve as a prequel to the development of a full strategic T&E Roadmap. Science and technology has been moving at an exponential pace, especially within disciplines critical to the CBD program. These primarily include the biological sciences, especially systems and synthetic biology and structural biology; information science, particularly bioinformatics; nanotechnology, specifically the ability to tailor nanomaterials from "the ground up, " and to design and fabricate devices on the nanoscale; and combinatorial chemistry. These rapid developments underpin both next generation threats and new countermeasure technologies that must be subjected to rigorous T&E before fielding.