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Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications

Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications
Author: R. C. Sobti
Publisher: Springer Nature
Total Pages: 496
Release: 2021-11-30
Genre: Medical
ISBN: 9811651051

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This book discusses the organ-specific systemic manifestations of COVID-19. The initial chapters of the book review the origin and evolution of the coronaviruses, followed by pathogenesis and immune response during COVID-19 infection. The book also provides insight into the role of angiotensin-converting enzyme 2 in the onset of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis. It summarizes the neurological aspects of SARS-CoV2, including transmission pathways, mechanisms of invasion into the nervous system, and mechanisms of neurological disease. It also delineates the association of severe disease with high blood plasma levels of inflammatory cytokines and inflammatory markers in SARS-CoV-2 infection. Lastly, it discusses the perturbation of gut microbiota by SARS-CoV-2 and uncovers the potential risk of virus infection on reproductive health.


COVID-19 Current Challenges and Future Perspectives

COVID-19 Current Challenges and Future Perspectives
Author: Anoop Kumar
Publisher: Bentham Science Publishers
Total Pages: 212
Release: 2021-03-03
Genre: Medical
ISBN: 9811498636

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COVID-19: Current Challenges and Future Perspectives informs readers about the current status of knowledge on COVID-19 infection. The book begins by presenting basic information about the history, epidemiology, pathogenesis, diagnosis, treatment and preventive measures against COVID-19. The second part of the book contains information about the repurposing of drugs, herbal medicines, and immunotherapy against COVID-19 infections. Integrating both general and advanced information about Sars-cov-2, this book updates a wide range of readers including students, researchers (virologists, pharmacologists), health care professionals (physicians, nurses, pharmacists, paramedics) and the general public on novel coronaviruses and COVID-19.


New Advances on Zika Virus Research

New Advances on Zika Virus Research
Author: Luis Martinez-Sobrido
Publisher: MDPI
Total Pages: 554
Release: 2019-04-02
Genre: Arctic medicine. Tropical medicine
ISBN: 3038977640

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Zika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family that historically has been associated with mild febrile illness. However, the recent outbreaks in Brazil in 2015 and its rapid spread throughout South and Central America and the Caribbean, together with its association with severe neurological disorders—including fetal microcephaly and Guillain-Barré syndrome in adults—have changed the historic perspective of ZIKV. Currently, ZIKV is considered an important public health concern that has the potential to affect millions of people worldwide. The significance of ZIKV in human health and the lack of approved vaccines and/or antiviral drugs to combat ZIKV infection have triggered a global effort to develop effective countermeasures to prevent and/or treat ZIKV infection. In this Special Issue of Viruses, we have assembled a collection of 32 research and review articles that cover the more recent advances on ZIKV molecular biology, replication and transmission, virus–host interactions, pathogenesis, epidemiology, vaccine development, antivirals, and viral diagnosis.


Reopening K-12 Schools During the COVID-19 Pandemic

Reopening K-12 Schools During the COVID-19 Pandemic
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 115
Release: 2020-11-08
Genre: Education
ISBN: 0309680077

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The COVID-19 pandemic has presented unprecedented challenges to the nation's K-12 education system. The rush to slow the spread of the virus led to closures of schools across the country, with little time to ensure continuity of instruction or to create a framework for deciding when and how to reopen schools. States, districts, and schools are now grappling with the complex and high-stakes questions of whether to reopen school buildings and how to operate them safely if they do reopen. These decisions need to be informed by the most up-to-date evidence about the SARS-CoV-2 virus that causes COVID-19; about the impacts of school closures on students and families; and about the complexities of operating school buildings as the pandemic persists. Reopening K-12 Schools During the COVID-19 Pandemic: Prioritizing Health, Equity, and Communities provides guidance on the reopening and operation of elementary and secondary schools for the 2020-2021 school year. The recommendations of this report are designed to help districts and schools successfully navigate the complex decisions around reopening school buildings, keeping them open, and operating them safely.


Lumpy Skin Disease

Lumpy Skin Disease
Author: Eeva S. M. Tuppurainen
Publisher: Springer
Total Pages: 99
Release: 2018-07-03
Genre: Medical
ISBN: 3319924117

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This book provides a comprehensive but concise overview on the economically important emerging cattle pox virus derived Lumpy Skin Disease, including the characteristics of causative agent, description of clinical signs in cattle, pathology and histopathology, immunity, geographical distribution, epidemiology and transmission pathways, control and eradication of the disease. In addition the recent developments in vaccination, mathematical modeling and risk assessment are discussed. Lumpy Skin Disease currently spreads aggressively across the Middle and Near East. The first incursion to the European Union territory occurred in Greece in autumn 2015. The book targets clinicians and field veterinarians in Lumpy Skin Disease affected regions, veterinary authorities as well as advanced students in veterinary medicine and virology.


Replication-Competent Reporter-Expressing Viruses

Replication-Competent Reporter-Expressing Viruses
Author: Luis Martinez-Sobrido
Publisher: MDPI
Total Pages: 339
Release: 2018-09-27
Genre: Biology (General)
ISBN: 3038422584

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This book is a printed edition of the Special Issue "Replication-Competent Reporter-Expressing Viruses" that was published in Viruses


Mathematical Modelling in Biomedicine

Mathematical Modelling in Biomedicine
Author: Vitaly Volpert
Publisher: MDPI
Total Pages: 224
Release: 2021-01-26
Genre: Mathematics
ISBN: 3039434934

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Mathematical modelling in biomedicine is a rapidly developing scientific discipline at the intersection of medicine, biology, mathematics, physics, and computer science. Its progress is stimulated by fundamental scientific questions and by the applications to public health. This book represents a collection of papers devoted to mathematical modelling of various physiological problems in normal and pathological conditions. It covers a broad range of topics including cardiovascular system and diseases, heart and brain modelling, tumor growth, viral infections, and immune response. Computational models of blood circulation are used to study the influence of heart arrhythmias on coronary blood flow and on operating modes for left-ventricle-assisted devices. Wave propagation in the cardiac tissue is investigated in order to show the influence of tissue heterogeneity and fibrosis. The models of tumor growth are used to determine optimal protocols of antiangiogenic and radiotherapy. The models of viral hepatitis kinetics are considered for the parameter identification, and the evolution of viral quasi-species is investigated. The book presents the state-of-the-art in mathematical modelling in biomedicine and opens new perspectives in this passionate field of research.


Stigma

Stigma
Author: Gerhard Falk
Publisher: Prometheus Books
Total Pages: 376
Release: 2010-04-06
Genre: Psychology
ISBN: 1615923969

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What is it in human nature that leads us to label some as insiders and stigmatize others as outsiders?Sociologist Gerhard Falk examines the social psychology that motivates this process of exclusion, focusing on the outcasts in contemporary American society and comparing current experience with examples from the past. Referring to the work of Emile Durkheim and Erving Goffman, Falk reviews the whole range of stigmatized people from the mentally ill to ordinary people with unpopular occupations, like undertakers and trash collectors. Amid the wide diversity of stigmatized persons, he finds two basic types of outsiders: the "existential" and the "achieved." The first group comprises those who are stigmatized because of their very existence, regardless of their specific actions: the mentally handicapped, for example. The second group describes those whose actions or life conditions have resulted in stigma: from high achievers (often subject to resentment) to criminals. Falk also looks at the ways in which writers past and present have dramatized stigmatized characters in literature.This fascinating overview of a long-standing and widespread social problem will be of interest to all those concerned about creating a more fair-minded society.


Debating Emerging Adulthood

Debating Emerging Adulthood
Author: Jeffrey Jensen Arnett
Publisher: Oxford University Press
Total Pages: 189
Release: 2011-01-14
Genre: Family & Relationships
ISBN: 0199757178

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The transition from adolescence to adulthood has undergone significant changes in recent decades. Unlike a half century ago, when young people in industrialized countries moved from adolescence into young adulthood in relatively short order at around age 20, now the decade from the late teens to the late twenties is seen as an extended time of self-focused exploration and education in pursuit of optimally fulfilling relationships and careers. Recognition of this new period is stronger than ever, but an important question remains: should emerging adulthood be considered a developmental stage, or a process?In Debating Emerging Adulthood: Stage or Process? two pairs of developmental psychologists take sides in a debate that is central to the very concept of emerging adulthood. Arnett and Tanner argue that as young people around the world share demographic similarities, such as longer education and later marriage, the years between the ages 18 and 25 are best understood as entailing a new life stage. However, because the experiences of emerging adults worldwide vary according to cultural context, educational attainment, and social class, these two scholars suggest that there may not be one but many different emerging adulthoods. An important issue for this burgeoning area of inquiry is to explore and describe this variation. In contrast, Hendry and Kloep assert that stage theories have never been able to explain individual transitions across the life course; in their view, stage theories-including the theory of emerging adulthood-ought to be abolished altogether, and explanations found for the processes and mechanisms that govern human change at any age. This engaging book maps out the argument of "stage or process" in detail, with vigorous disagreements, conflicting alternatives, and some leavening humor, ultimately even finding some common ground. Debating Emerging Adulthood is an absolute must-read for developmental psychologists as well as anyone interested in this indisputably important time of life.


Electrochemical Biosensors

Electrochemical Biosensors
Author: Serge Cosnier
Publisher: CRC Press
Total Pages: 405
Release: 2015-01-26
Genre: Science
ISBN: 9814411477

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Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy