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Current Topics in Clinical Radiobiology of Tumors

Current Topics in Clinical Radiobiology of Tumors
Author: Hans-Peter Beck-Bornholdt
Publisher: Springer Science & Business Media
Total Pages: 364
Release: 2012-12-06
Genre: Medical
ISBN: 3642849180

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The impact of basic science radiobiological research is now being recognized of significant importance in clinical radiation oncology. Observations made in the laboratory using animals as'well as tissue culture have led to a better biologic understanding of techniques for altered fractionation, techniques for measuring tumor cell proliferation, the possi bilities and limitations of methods for evaluation of nonrandomized clinical studies in deriving time dose relationships for human tumors as well as a better understanding of repair kinetics in mammalian cells, fractionation sensitivity and the major impact oftechnologies to improve local/regional control with the subsequent impact on survival. These findings have led to changes in treatment schedules and have led to further close cooperation among the radiation oncologists and radiation biologists. Well support research efforts in radiation biology have a major and significant impact on the clinical care of the cancer patient. Studies that originated in the laboratory are now finding their way into clinical practice resulting in better local and regional control and improved number of patients surviving without disease.


Current Topics in Clinical Radiobiology of Tumors

Current Topics in Clinical Radiobiology of Tumors
Author: Hans-Peter Beck-Bornholdt
Publisher: Springer
Total Pages: 152
Release: 2011-12-28
Genre: Medical
ISBN: 9783642849190

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The impact of basic science radiobiological research is now being recognized of significant importance in clinical radiation oncology. Observations made in the laboratory using animals as'well as tissue culture have led to a better biologic understanding of techniques for altered fractionation, techniques for measuring tumor cell proliferation, the possi bilities and limitations of methods for evaluation of nonrandomized clinical studies in deriving time dose relationships for human tumors as well as a better understanding of repair kinetics in mammalian cells, fractionation sensitivity and the major impact oftechnologies to improve local/regional control with the subsequent impact on survival. These findings have led to changes in treatment schedules and have led to further close cooperation among the radiation oncologists and radiation biologists. Well support research efforts in radiation biology have a major and significant impact on the clinical care of the cancer patient. Studies that originated in the laboratory are now finding their way into clinical practice resulting in better local and regional control and improved number of patients surviving without disease.


Basic Clinical Radiobiology Fourth Edition

Basic Clinical Radiobiology Fourth Edition
Author: Michael C. Joiner
Publisher: CRC Press
Total Pages: 392
Release: 2009-03-27
Genre: Medical
ISBN: 0340929669

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This concise but comprehensive textbook sets out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, the fourth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. New topics for the fourth edition include chapters on the mechanisms of cell death, biological response modifiers, and biological image guided radiotherapy, with major revisions to sections on the molecular basis of the radiation response, tumour hypoxia and the dose-rate effect. A variety of new authors have contributed to this revision, who, together with the new Editorial team, have used their significant international teaching experience to ensure the content remains clear and comprehensive, and as valuable to the trainee as it is to the established radiation oncologist. With the fourth edition we will see the most radical change so far - as Professor Gordon Steel has retired as Editor and has been replaced by Bert van der Kogel, the current current course director for the above-mentioned course, plus Michael Joiner, who is the head of the Radiation Biology Program at the Wayne State University and is the Associate Editor of the International Journal of Radiation Biology.


Advances in Radiation Therapy

Advances in Radiation Therapy
Author: M. Guckenberger
Publisher: Karger Medical and Scientific Publishers
Total Pages: 146
Release: 2018-04-12
Genre: Medical
ISBN: 3318063622

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Developments in radiation oncology have been key to the tremendous progress made in the field in recent years. The combination of optimal systemic treatment and local therapy has resulted in continuing improved outcomes of cancer therapy. This progress forms the basis for current pre-clinical and clinical research which will strengthen the position of radiation oncology as an essential component of oncological care. This book summarizes recent advances in radiotherapy research and clinical patient care. Topics include radiobiology, radiotherapy technology, and particle therapy. Chapters cover a summary and analysis of recent developments in the search for biomarkers for precision radiotherapy, novel imaging possibilities and treatment planning, and advances in understanding the differences between photon and particle radiotherapy. Advances in Radiation Therapy is an invaluable source of information for scientists and clinicians working in the field of radiation oncology. It is also a relevant resource for those interested in the broad topic of radiotherapy in general.


Contemporary Topics in Radiation Medicine, Part I: Current Issues and Techniques

Contemporary Topics in Radiation Medicine, Part I: Current Issues and Techniques
Author: Ravi A. Chandra
Publisher: Elsevier Health Sciences
Total Pages: 233
Release: 2019-11-02
Genre: Medical
ISBN: 0323683274

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This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Ravi A. Chandra, Lisa A. Kachnic, Charles R. Thomas, Jr., is part one of a two-part issue focused on Contemporary Topics in Radiation Medicine. Topics include, but are not limited to, Basic Medical Physics, Basic Radiobiology, Modern Radiation Treatment Planning & Delivery, Advanced Imaging Techniques in Diagnosis and Tx, Particle Therapy/Protons, SRS/SBRT, Modern Brachytherapy, Immunotherapy/Abscopal, Nanotechnology, Bioinformatics & Artificial Intelligence, Quality-of-life & Outcomes, Normal Tissue Issues and Toxicity, Radiation Modifiers, and Health Economics/Disparities.


Radiobiology of Glioblastoma

Radiobiology of Glioblastoma
Author: Luigi Pirtoli
Publisher: Springer
Total Pages: 314
Release: 2016-06-06
Genre: Medical
ISBN: 3319283057

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This text properly considers the most recent and relevant advances in molecular RB of GB, taking into account the related topics of pathobiology, and underscores the most promising translational perspectives from the preclinical to the clinical domain. Section I (From Bedside to Bench) discusses conditions associated with RT resistance of GB and the consequent RB hints, technology improvements intended to overcome RT-resistance of GB, mathematical modeling of RB parameters from clinical studies, the present impact of molecular prognostic factors in therapy of GB, and RT tolerance of normal brain. Section II (Preclinical Research and Pathobiology Topics) presents the traditional and mechanistic/molecular approaches to RB of GB, genetic and epigenetic studies on GB, issues of cell-death pathways, stem-like cells, invasiveness, tumor microenvironment, hypoxia, mi-RNA manipulations, and nanoparticle technology. Section III (Translational Perspectives) presents RB issues related to molecular profiling and classification of GB as frames of reference for clinical studies, translational perspectives of gene therapy, evolving protocols based on pre-clinical data and large data-bases and ontologic models. Radiobiology of Glioblastoma: Recent Advances and Related Pathobiology will be of great value to pathologists, medical oncologists, radiation oncologists as well as basic researchers and clinical investigators.


Radiobiology for the Radiologist

Radiobiology for the Radiologist
Author: Eric J. Hall
Publisher: Lippincott Williams & Wilkins
Total Pages: 908
Release: 2012-03-28
Genre: Medical
ISBN: 1451154186

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In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.


Radiation Oncology

Radiation Oncology
Author: Murat Beyzadeoglu
Publisher: Springer Science & Business Media
Total Pages: 498
Release: 2012-04-12
Genre: Medical
ISBN: 3642279880

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'Radiation Oncology: MCQs for Exams' (ROME) will cover the essential aspects of radiation physics, radiobiology, and clinical radiation oncology designed to meet the needs of a large scale of examinees. Topics of this new book will be in the order of our previous "Basic Radiation Oncology" (Springer, 2010) with additional two new chapters (Pediatric tumors and Rare tumors-Benign Diseases) making a total of 15 chapters and instead of old style question and answer format,current MCQ examination pattern helpful for both oral exams and written exams is used in this comprehensive bedside recall book complementing the "Basic Radiation Oncology"1st Edition.


Basic Clinical Radiobiology, 3Ed

Basic Clinical Radiobiology, 3Ed
Author: George Gordon Steel
Publisher: CRC Press
Total Pages: 280
Release: 2002-07-31
Genre: Medical
ISBN: 9780340807835

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This concise, but comprehensive textbook sets out all the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology. The fully updated 3rd edition continues to discuss the basis of radiation therapy and presents the principles and significant scientific developments that underlie current attempts to improve the radiotherapeutic managemnet of all cancers. New topics in the 3rd edition include chapters on volume effects in normal tissues and the L-Q approach in clinical practice, with major revisions to sections on cell proliferation, radiation cytogenetics, radiotherapy-related morbidity, hyperfractionation and individualisation of radiotherapy. The book continues to provide invaluable advice for trainee and practising radiation oncologists from a team of internationally respected contributors and draws on the considerable experience of the Editor, gained during his time as Course Director of the annual ESTRO course in Basic Clinical Radiobiology.


Radiobiology for the Radiologist

Radiobiology for the Radiologist
Author: Eric J. Hall
Publisher: Lippincott Williams & Wilkins
Total Pages: 572
Release: 2006
Genre: Medical
ISBN: 9780781741514

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The updated Sixth Edition of this popular text will remain the first choice for those who need current, clinically relevant information on how radiation affects the human body. Written by practicing, active radiobiologists, the book brings together basic laboratory research and practical, clinical applications. The easy-to-read text and informative illustrations ensure comprehension, and summaries at the end of each chapter facilitate quick review. The first section covers topics applicable to diagnostic radiology, nuclear medicine, and radiation oncology; the second section offers material specifically for radiation oncologists. This edition includes new material about doses and risks in interventional radiology and cardiology.