Crispr In Animals And Animal Models PDF Download
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Author | : |
Publisher | : Academic Press |
Total Pages | : 150 |
Release | : 2017-11-10 |
Genre | : Science |
ISBN | : 0128125071 |
Download CRISPR in Animals and Animal Models Book in PDF, ePub and Kindle
CRISPR in Animals and Animal Models, Volume 152, the latest release in the Progress in Molecular Biology and Translational Science series, explores the genome editing CRISPR system in cells and animal models, its applications, the uses of the CRISPR system, and the past, present and future of CRISPR genome editing. Topics of interest in this updated volume include a section on CRISPR history, The genome editing revolution, Programming CRISPR and its applications, CRISPR Delivery methods, CRISPR libraries and screening, CRISPR investigation in haploid cells, CRISPR in the generation of transgenic animals, CRISPR therapeutics, and Promising strategies and present challenges. Accessible to students and researchers alike Written by leading authorities in the field
Author | : |
Publisher | : Academic Press |
Total Pages | : 226 |
Release | : 2019-07-30 |
Genre | : Medical |
ISBN | : 012816574X |
Download Cellular and Animal Models in Human Genomics Research Book in PDF, ePub and Kindle
Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth. Provides a thorough, accessible resource that helps researchers and students employ cellular and animal models in their own genetic and genomic studies Offers guidance on how to effectively interpret the results and significance of genetic and genomic model studies for human health Features chapters from international experts in the use of specific cellular and animal models, including yeast, worms, flies, fish, mice, and large animals, among other organisms
Author | : Jun Song |
Publisher | : Frontiers Media SA |
Total Pages | : 186 |
Release | : 2022-02-18 |
Genre | : Science |
ISBN | : 2889744426 |
Download Genome Editing Applications in Animal Research Book in PDF, ePub and Kindle
Author | : Izuho Hatada |
Publisher | : Springer Nature |
Total Pages | : 396 |
Release | : 2023-02-11 |
Genre | : Science |
ISBN | : 1071630164 |
Download Genome Editing in Animals Book in PDF, ePub and Kindle
This second edition provides new and updated protocols that can be used for generation of knockout animals. Chapters guide the reader through basic protocols for three genome editing technologies, target design tools, and specific protocols for each animal. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Genome Editing in Animals: Methods and Protocols, Second Edition aims to be a useful practical guide to researches to help further their study in this field.
Author | : Michael G. Katze |
Publisher | : Academic Press |
Total Pages | : 368 |
Release | : 2015-12-30 |
Genre | : Medical |
ISBN | : 0128011742 |
Download Viral Pathogenesis Book in PDF, ePub and Kindle
Viral Pathogenesis: From Basics to Systems Biology, Third Edition, has been thoroughly updated to cover topical advances in the evolving field of viral pathogenesis, while also providing the requisite classic foundational information for which it is recognized. The book provides key coverage of the newfound ability to profile molecular events on a system-wide scale, which has led to a deeper understanding of virus-host interactions, host signaling and molecular-interaction networks, and the role of host genetics in determining disease outcome. In addition, the content has been augmented with short chapters on seminal breakthroughs and profiles of their progenitors, as well as short commentaries on important or controversial issues in the field. Thus, the reader will be given a view of virology research with perspectives on issues such as biomedical ethics, public health policy, and human health. In summary, the third edition will give the student a sense of the exciting new perspectives on viral pathogenesis that have been provided by recent developments in genomics, computation, modeling, and systems biology. Covers all aspects of viral infection, including viral entry, replication, and release, as well as innate and adaptive immunity and viral pathogenesis Provides a fresh perspective on the approaches used to understand how viruses cause disease Features molecular profiling techniques, whole genome sequencing, and innovative computational methods Highlights the use of contemporary approaches and the insights they provide to the field
Author | : Yongye Huang |
Publisher | : Frontiers Media SA |
Total Pages | : 155 |
Release | : 2023-06-21 |
Genre | : Science |
ISBN | : 2832526888 |
Download Applying large animals for developmental study and disease modeling Book in PDF, ePub and Kindle
Author | : Ranbir Chander Sobti |
Publisher | : Academic Press |
Total Pages | : 504 |
Release | : 2021-12-08 |
Genre | : Science |
ISBN | : 0323910440 |
Download Advances in Animal Experimentation and Modeling Book in PDF, ePub and Kindle
Exploration in Laboratory Animal Sciences Understanding Life Phenomena updates our knowledge about the newer technologies such as molecular biology, genomics including sequencing, proteomics, transcriptomics, cell culture, stem cell culture, transgenesis and their translation to understand systematics and phylogeny of laboratory animals at molecular level. In seven sections Exploration in Laboratory Animal Sciences Understanding Life Phenomena resolves issues of conservation, applications in environment monitoring, production of drugs and others. Comparative research has enabled use of domestic animal models that translate the advances in basic biosciences to the schemes for human welfare including medicine. Molecular geneticists are unravelling the complexities of mammalian genes and the field of biotechnology is maturing at a fast pace. Additionally, research focused on immunology and animal behavior offer new insight into ways of enhancing animal welfare. The rise in consumption of animal proteins in addition to the challenges of sustaining our natural resources has given animal scientists a vast array of opportunities to engage in integrative systems-based research for meeting the challenges that behold us. Exploration in Laboratory Animal Sciences Understanding Life Phenomena also discusses the manipulation of animals as factories for the production of safe foods, drugs, and sensors and others to meet the contemporary challenges faced by mankind in the new world order created by pandemic of Covid 19. It also includes several chapters on the causation and management of certain diseases and impact of microbes on life. Provides insight to newer and futuristic technologies to understand disease process and drug design by animal models Addresses a wide variety of species and covers a wide variety of topics (such as animal species, the laboratory setting, regulatory guidelines, and ethical considerations) to fully prepare for work with all types of animals Gives a perspective on laboratory animal use that allows to explain the benefits of animal use as required by veterinary technology program accreditation procedure Includes examples of animal bio-technological techniques (including stem cell and tissue engineering) for their applications to humanity Offers new insight into ways of enhancing animal welfare by the inclusion of research results focused on immunology and laboratory animal behavior
Author | : Kathrin Herrmann |
Publisher | : BRILL |
Total Pages | : 749 |
Release | : 2019-04-30 |
Genre | : Philosophy |
ISBN | : 9004391193 |
Download Animal Experimentation: Working Towards a Paradigm Change Book in PDF, ePub and Kindle
Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.
Author | : George M Church |
Publisher | : Basic Books |
Total Pages | : 305 |
Release | : 2014-04-08 |
Genre | : Science |
ISBN | : 0465038654 |
Download Regenesis Book in PDF, ePub and Kindle
A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.
Author | : Rodolphe Barrangou |
Publisher | : Springer Science & Business Media |
Total Pages | : 300 |
Release | : 2012-12-13 |
Genre | : Science |
ISBN | : 364234657X |
Download CRISPR-Cas Systems Book in PDF, ePub and Kindle
CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.