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| Author | : Charlene A. McQueen |
| Publisher | : |
| Total Pages | : 568 |
| Release | : 2010 |
| Genre | : Toxicology |
| ISBN | : 9780080468815 |
| Author | : |
| Publisher | : |
| Total Pages | : |
| Release | : 1997 |
| Genre | : Toxicology |
| ISBN | : |
| Author | : H.E. Lowndes |
| Publisher | : Pergamon |
| Total Pages | : 564 |
| Release | : 1999-08-18 |
| Genre | : Medical |
| ISBN | : 9780080429762 |
Neurotoxicology is among the fastest growing of the toxicological disciplines. Recent refinements of neuropathologic techniques, meticulous validation of behavioral tests, and introduction of the tools of molecular biology have led to rapid progress in our understanding of the mechanisms and consequences of neurotoxic injury. This volume is intended to provide the reader with an appreciation of the scope of approaches taken in the mechanistic study of neurotoxic agents. The volume's 31 chapters, each contributed by recognized experts, are divided into three sections. Section 1 addresses the basic anatomical and biochemical components of the nervous system, with special attention placed on those areas where existing or emerging data have demonstrated toxic actions. This section is directed towards the nonspecialists, offering overviews of topics in neuroscience, as well as contemporary reviews of selected topics for researchers in the field. Section 2 focuses on neurobehavioral toxicology and alterations of the special issues. Specific behavioral domains and the functional consequences of their perturbation are discussed in detail. Particular emphasis has been given to research methodologies in neurobehavioral toxicology especially the appropriate use, limitations, and interpretations. Section 3 provides a survey of selected classes of compounds demonstrated to have adverse effects on nervous system structure and function. It is intended to provide current reviews of chemical-specific neurotoxicity for practitioners in neurotoxicity.
| Author | : |
| Publisher | : |
| Total Pages | : |
| Release | : 1997 |
| Genre | : Toxicology |
| ISBN | : |
| Author | : H.E. Lowndes |
| Publisher | : Pergamon |
| Total Pages | : 0 |
| Release | : 1999-08-04 |
| Genre | : Medical |
| ISBN | : 9780080429762 |
Neurotoxicology is among the fastest growing of the toxicological disciplines. Recent refinements of neuropathologic techniques, meticulous validation of behavioral tests, and introduction of the tools of molecular biology have led to rapid progress in our understanding of the mechanisms and consequences of neurotoxic injury. This volume is intended to provide the reader with an appreciation of the scope of approaches taken in the mechanistic study of neurotoxic agents. The volume's 31 chapters, each contributed by recognized experts, are divided into three sections. Section 1 addresses the basic anatomical and biochemical components of the nervous system, with special attention placed on those areas where existing or emerging data have demonstrated toxic actions. This section is directed towards the nonspecialists, offering overviews of topics in neuroscience, as well as contemporary reviews of selected topics for researchers in the field. Section 2 focuses on neurobehavioral toxicology and alterations of the special issues. Specific behavioral domains and the functional consequences of their perturbation are discussed in detail. Particular emphasis has been given to research methodologies in neurobehavioral toxicology especially the appropriate use, limitations, and interpretations. Section 3 provides a survey of selected classes of compounds demonstrated to have adverse effects on nervous system structure and function. It is intended to provide current reviews of chemical-specific neurotoxicity for practitioners in neurotoxicity.
| Author | : Clifford L. Mitchell |
| Publisher | : Raven Press (ID) |
| Total Pages | : 402 |
| Release | : 1982 |
| Genre | : Behavior |
| ISBN | : |
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 449 |
| Release | : 1990-02-01 |
| Genre | : Science |
| ISBN | : 0309040477 |
Exposure to toxic chemicalsâ€"in the workplace and at homeâ€"is increasing every day. Human behavior can be affected by such exposure and can give important clues that a person or population is in danger. If we can understand the mechanisms of these changes, we can develop better ways of testing for toxic chemical exposure and, most important, better prevention programs. This volume explores the emerging field of neurobehavioral toxicology and the potential of behavior studies as a noninvasive and economical means for risk assessment and monitoring. Pioneers in this field explore its promise for detecting environmental toxins, protecting us from exposure, and treating those who are exposed.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 167 |
| Release | : 1992-02-01 |
| Genre | : Science |
| ISBN | : 0309045312 |
Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
| Author | : Harold Zenick |
| Publisher | : |
| Total Pages | : 180 |
| Release | : 1977 |
| Genre | : Behavioral toxicology |
| ISBN | : |
| Author | : Bernard Weiss |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 475 |
| Release | : 2013-03-09 |
| Genre | : Science |
| ISBN | : 1468428594 |
Behavioral toxicology is a young discipline in the United States; so young, in fact, that this is one of its first books. Behavioral questions are bound to play a major role in future scientific work and governmental decisions involving the health effects of environmental contaminants and other chemicals. This role springs from two key problems that face scientists and public agencies required to set acceptable exposure standards or to determine criteria for the toxicity of therapeutic chemicals: How do you evaluate effects that may show up only as subtle functional disturbances? And how do you de tect toxic effects early enough so that they may still be reversible, before they produce major damage? The contributions in this book come from a collection of scientists whose interests span a wide variety of problem areas. The focus is largely on me thodological issues because they represent the most immediate concern of the discipline. We expect that this collection of papers will represent a useful source book for behavioral toxicology for some time. For the past few years, the University of Rochester's Department of Radiation Biology and Biophysics has sponsored a series of international conferences on chemical toxicity, partly as a response to concern over the con sequences to health of the rich chemical soup in which we live. This book is based upon presentations made to the fifth of the series. Held in June, 1972, it was the first formal meeting devoted to behavioral toxicology in this country.
