Biotechnology Plasma Proteins PDF Download
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Author | : Roger L. Lundblad |
Publisher | : CRC Press |
Total Pages | : 460 |
Release | : 2012-08-08 |
Genre | : Medical |
ISBN | : 1439850275 |
Download Biotechnology of Plasma Proteins Book in PDF, ePub and Kindle
The fractionation of human blood plasma can be considered to be a mature industry, with the basic technology, alcohol fractionation, dating back at least to the 1940s. Many of the products described in the current work have been approved biologics since the 1950s. The information gathered from the development of plasma proteins has proved vital to
Author | : Joseph Bertolini |
Publisher | : John Wiley & Sons |
Total Pages | : 518 |
Release | : 2012-12-26 |
Genre | : Medical |
ISBN | : 0470924314 |
Download Production of Plasma Proteins for Therapeutic Use Book in PDF, ePub and Kindle
Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the current state of knowledge about the function, use, and production of blood plasma proteins. In addition to details of the operational requirements for the production of plasma derivatives, the book describes the biology, development, research, manufacture, and clinical indications of essentially all plasma proteins with established clinical use or therapeutic potential. Production of Plasma Proteins for Therapeutic Use covers the key aspects of the plasma fractionation industry in five sections: Section 1: Introduction to Plasma Fractionation initially describes the history of transfusion and then covers the emergence of plasma collection and fractionation from its earliest days to the present time, with the commercial and not-for-profit sectors developing into a multi-billion dollar industry. Section 2: Plasma Proteins for Therapeutic Use contains 24 chapters dedicated to specific plasma proteins, including coagulation factors, albumin, immunoglobulin, and a comprehensive range of other plasma-derived proteins with therapeutic indications. Each chapter discusses the physiology, biochemistry, mechanism of action, and manufacture of each plasma protein including viral safety issues and clinical uses. Section 3: Pathogen Safety of Plasma Products examines issues and procedures for enhancing viral safety and reducing the risk of transmissible spongiform encephalopathy transmission. Section 4: The Pharmaceutical Environment Applied to Plasma Fractionation details the requirements and activities associated with plasma collection, quality assurance, compliance with regulatory requirements, provision of medical affairs support, and the manufacture of plasma products. Section 5: The Market for Plasma Products and the Economics of Fractionation reviews the commercial environment and economics of the plasma fractionation industry including future trends, highlighting regions such as Asia, which have the potential to exert a major influence on the plasma fractionation industry in the twenty-first century.
Author | : Albertini |
Publisher | : Hart Associates |
Total Pages | : |
Release | : 1991-01-01 |
Genre | : |
ISBN | : 9780805552508 |
Download Biotechnology Plasma Proteins Book in PDF, ePub and Kindle
Author | : Alberto Albertini |
Publisher | : S Karger Ag |
Total Pages | : 0 |
Release | : 1991 |
Genre | : Medical |
ISBN | : 9783805552509 |
Download Biotechnology of Plasma Proteins Book in PDF, ePub and Kindle
Author | : Claude Rivat |
Publisher | : John Libbey Eurotext |
Total Pages | : 356 |
Release | : 1993 |
Genre | : Medical |
ISBN | : 9782742000074 |
Download Biotechnology of Blood Proteins Book in PDF, ePub and Kindle
There are today five major proteins in plasma fractioning. In the near future, other fractions could also be used as therapeutic agents. But perhaps they could be used for alternative, non-therapeutic applications? For example, producing human culture media with specific ingredients for biotechnology research might also be of use. Whatever the future may hold, there is one essential question: in today's world of cellular and genetic engineering, are extracted therapeutic proteins still of any relevance? For a clear and up-to-date view of recent developments in blood-protein-separation technology, this book will prove an invaluable resource.
Author | : Johann Schaller |
Publisher | : John Wiley & Sons |
Total Pages | : 538 |
Release | : 2008-05-23 |
Genre | : Science |
ISBN | : 9780470724361 |
Download Human Blood Plasma Proteins Book in PDF, ePub and Kindle
Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include: introduction to blood components and blood plasma proteins blood plasma protein domains, motifs and repeats blood plasma protein families and posttranslational modifications blood coagulation and fibrinolysis the complement system the immune system enzymes inhibitors lipoproteins hormones cytokines and growth factors transport and storage The information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure. Attractively presented in full colour, Human Blood Plasma Proteins is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.
Author | : Jack Goldstein |
Publisher | : Newnes |
Total Pages | : 478 |
Release | : 2014-06-28 |
Genre | : Science |
ISBN | : 1483294463 |
Download Biotechnology of Blood Book in PDF, ePub and Kindle
Biotechnology of Blood presents research on applications of biotechnology to blood and its components. The book is organized into four parts. Part I begins with an overview of the blood business in order to provide background of the industry, to identify problems, and perhaps some solutions that rely on the scientific advances made possible by biotechnology. This is followed by studies on the storage and preservation of red blood cells; autologous blood salvage procedures; the development procedures to provide a constant supply of blood group O; and the development of blood substitutes. Part II on plasma fractions includes studies on the preparation of plasma fractions, recombinant antihemophilic factors, and fibrinogen. Part III on the regulation of blood cell products includes studies such as hematopoietic stem cell processing and storage; and long-term bone marrow cell cultures. Part IV on blood-borne diseases examines the inactivation of viruses found with plasma proteins and viruses found with cellular components.
Author | : Frank Putnam |
Publisher | : Elsevier |
Total Pages | : 633 |
Release | : 2012-12-02 |
Genre | : Medical |
ISBN | : 0323161464 |
Download The Plasma Proteins V3 Book in PDF, ePub and Kindle
The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume III is an eight-chapter treatise that describes the plasma proteins in a systematic integrated manner. This book presents first the perspectives and global outlook at plasma proteins, followed by a series of chapters on the well-characterized major proteins, with particular emphasis on immunoglobulins. Other chapters are devoted to the integrated systems of plasma proteins, especially their structure, function, and genetic control. A chapter describes the plasma protein fractionation. The remaining chapters introduce the clinical relevance of the plasma proteins. This book will be of great value to biologists, geneticists, clinicians, and researchers.
Author | : Barbara H. Bowman |
Publisher | : Elsevier |
Total Pages | : 298 |
Release | : 2014-05-10 |
Genre | : Science |
ISBN | : 1483216500 |
Download Hepatic Plasma Proteins Book in PDF, ePub and Kindle
Hepatic Plasma Proteins: Mechanisms of Function and Regulation covers the mechanisms of function, inherited variation, and regulation of genes encoding the plasma proteins synthesized in the liver. The book discusses the physiological and clinical implications of human plasma protein abnormalities; the acute-phase reactants; and the variety of human plasma proteinase inhibitors. The text also describes the plasma protein vehicles (transferrin, ceruloplasmin, transthyretin, haptoglobin, hemopexin, and the vitamin D binding protein), as well as cytokines and transcription factors involved in the regulatory process. The protein and gene anatomies are discussed in terms of evolutionary relationships and genetic variations, especially those with mutations causing clinical manifestations. The book also encompasses the mechanisms responsible for tissue specific and developmental expression of plasma protein genes. Geneticists, biochemists, molecular biologists, physicians, and other students of biology will find the book invaluable.
Author | : Frank Putnam |
Publisher | : Elsevier |
Total Pages | : 433 |
Release | : 2012-12-02 |
Genre | : Medical |
ISBN | : 032316174X |
Download The Plasma Proteins V5 Book in PDF, ePub and Kindle
The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume V explores the contribution of molecular biology and gene cloning approaches to the advancement of plasma protein structure, function, and genomic organization studies. This volume is composed of five chapters and begins with a discussion on the DNA sequences and chromosomal location of plasma protein genes, specifically the cloning and sequencing of immunoglobulin genes. These topics are followed by a discussion on the advances in relation to discovered genetic variants present either as normal phenotypes or in dyslipoproteinemic states associated with cardiovascular disease. A chapter highlights the application of molecular biology techniques to the study of gene structure and the translational and maturation steps of every major plasma apolipoprotein. Another chapter emphasizes the unique features of protein structure and the conformational changes that characterize the assembly of macromolecular complexes in plasma and on cell surfaces. The concluding chapter provides a comprehensive review of the integration of molecular biology, physiology, and pathology of plasma proteins and their response in inflammation. This book will be of great value to molecular biologists, physiologists, pathologists, and clinicians.