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Biological Pattern Discovery With R: Machine Learning Approaches

Biological Pattern Discovery With R: Machine Learning Approaches
Author: Zheng Rong Yang
Publisher: World Scientific
Total Pages: 462
Release: 2021-09-17
Genre: Science
ISBN: 9811240132

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This book provides the research directions for new or junior researchers who are going to use machine learning approaches for biological pattern discovery. The book was written based on the research experience of the author's several research projects in collaboration with biologists worldwide. The chapters are organised to address individual biological pattern discovery problems. For each subject, the research methodologies and the machine learning algorithms which can be employed are introduced and compared. Importantly, each chapter was written with the aim to help the readers to transfer their knowledge in theory to practical implementation smoothly. Therefore, the R programming environment was used for each subject in the chapters. The author hopes that this book can inspire new or junior researchers' interest in biological pattern discovery using machine learning algorithms.


Biological Pattern Discovery with R

Biological Pattern Discovery with R
Author: Yang Rong Zheng
Publisher:
Total Pages: 462
Release: 2021
Genre: Biological systems
ISBN: 9789811240126

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Advances In Genomic Sequence Analysis And Pattern Discovery

Advances In Genomic Sequence Analysis And Pattern Discovery
Author: Laura Elnitski
Publisher: World Scientific
Total Pages: 236
Release: 2011-01-19
Genre: Science
ISBN: 9814462640

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Mapping the genomic landscapes is one of the most exciting frontiers of science. We have the opportunity to reverse engineer the blueprints and the control systems of living organisms. Computational tools are key enablers in the deciphering process. This book provides an in-depth presentation of some of the important computational biology approaches to genomic sequence analysis. The first section of the book discusses methods for discovering patterns in DNA and RNA. This is followed by the second section that reflects on methods in various ways, including performance, usage and paradigms.


Pattern Discovery in Biological Data Sets

Pattern Discovery in Biological Data Sets
Author: Stanislav Plamenov Angelov
Publisher:
Total Pages: 236
Release: 2007
Genre:
ISBN: 9781109985016

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There are two main approaches for extracting knowledge from sequence data. One approach compares newly acquired data with possibly, already annotated data under the assumption that data similarity implies functional similarity. The second approach mines the data for frequently occurring or surprising patterns. Such patterns are unlikely to occur at random and pinpoint candidates for further laboratory investigations.


Discriminative Pattern Discovery on Biological Networks

Discriminative Pattern Discovery on Biological Networks
Author: Fabio Fassetti
Publisher: Springer
Total Pages: 51
Release: 2017-09-01
Genre: Computers
ISBN: 3319634771

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This work provides a review of biological networks as a model for analysis, presenting and discussing a number of illuminating analyses. Biological networks are an effective model for providing insights about biological mechanisms. Networks with different characteristics are employed for representing different scenarios. This powerful model allows analysts to perform many kinds of analyses which can be mined to provide interesting information about underlying biological behaviors. The text also covers techniques for discovering exceptional patterns, such as a pattern accounting for local similarities and also collaborative effects involving interactions between multiple actors (for example genes). Among these exceptional patterns, of particular interest are discriminative patterns, namely those which are able to discriminate between two input populations (for example healthy/unhealthy samples). In addition, the work includes a discussion on the most recent proposal on discovering discriminative patterns, in which there is a labeled network for each sample, resulting in a database of networks representing a sample set. This enables the analyst to achieve a much finer analysis than with traditional techniques, which are only able to consider an aggregated network of each population.


Pattern Recognition in Computational Molecular Biology

Pattern Recognition in Computational Molecular Biology
Author: Mourad Elloumi
Publisher: John Wiley & Sons
Total Pages: 655
Release: 2015-11-30
Genre: Technology & Engineering
ISBN: 1119078857

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A comprehensive overview of high-performance pattern recognition techniques and approaches to Computational Molecular Biology This book surveys the developments of techniques and approaches on pattern recognition related to Computational Molecular Biology. Providing a broad coverage of the field, the authors cover fundamental and technical information on these techniques and approaches, as well as discussing their related problems. The text consists of twenty nine chapters, organized into seven parts: Pattern Recognition in Sequences, Pattern Recognition in Secondary Structures, Pattern Recognition in Tertiary Structures, Pattern Recognition in Quaternary Structures, Pattern Recognition in Microarrays, Pattern Recognition in Phylogenetic Trees, and Pattern Recognition in Biological Networks. Surveys the development of techniques and approaches on pattern recognition in biomolecular data Discusses pattern recognition in primary, secondary, tertiary and quaternary structures, as well as microarrays, phylogenetic trees and biological networks Includes case studies and examples to further illustrate the concepts discussed in the book Pattern Recognition in Computational Molecular Biology: Techniques and Approaches is a reference for practitioners and professional researches in Computer Science, Life Science, and Mathematics. This book also serves as a supplementary reading for graduate students and young researches interested in Computational Molecular Biology.


Bio-kernel Machines And Applications

Bio-kernel Machines And Applications
Author: Zheng Rong Yang
Publisher: World Scientific
Total Pages: 267
Release: 2024-03-06
Genre: Computers
ISBN: 981128735X

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Due to its capability of handling very complex problems and its high flexibility in adapting to different algorithms, the kernel machine plays a crucial role in machine learning.Bio-Kernel Machines and Applications will introduce a new type of kernel machine for the exploration and modeling between the genotypic inherent structures of short protein sequences or nucleic sequences and the phenotypic biological properties or functions of proteins or nucleotides.The book seeks to establish the fundamentals of the bio-kernel machines by presenting the basic principle and theory of the kernel machine and the various formats of kernel machines, such as string kernel machines adapted for biological applications. The book will also introduce several biological applications of the mutation matrices, demonstrating how mutation matrices can enhance the efficiency and biological relevance of machine learning models applied in specific biological problems.Through analyzing current applications of bio-kernel machines, readers will delve into the advantages of the bio-kernel machines and explore how bio-kernel machines can be further enhanced to tackle a wide spectrum of biological challenges and pave the way for future advancements.


Pattern Recognition in Computational Molecular Biology

Pattern Recognition in Computational Molecular Biology
Author: Mourad Elloumi
Publisher: John Wiley & Sons
Total Pages: 654
Release: 2015-12-29
Genre: Technology & Engineering
ISBN: 1118893689

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A comprehensive overview of high-performance pattern recognition techniques and approaches to Computational Molecular Biology This book surveys the developments of techniques and approaches on pattern recognition related to Computational Molecular Biology. Providing a broad coverage of the field, the authors cover fundamental and technical information on these techniques and approaches, as well as discussing their related problems. The text consists of twenty nine chapters, organized into seven parts: Pattern Recognition in Sequences, Pattern Recognition in Secondary Structures, Pattern Recognition in Tertiary Structures, Pattern Recognition in Quaternary Structures, Pattern Recognition in Microarrays, Pattern Recognition in Phylogenetic Trees, and Pattern Recognition in Biological Networks. Surveys the development of techniques and approaches on pattern recognition in biomolecular data Discusses pattern recognition in primary, secondary, tertiary and quaternary structures, as well as microarrays, phylogenetic trees and biological networks Includes case studies and examples to further illustrate the concepts discussed in the book Pattern Recognition in Computational Molecular Biology: Techniques and Approaches is a reference for practitioners and professional researches in Computer Science, Life Science, and Mathematics. This book also serves as a supplementary reading for graduate students and young researches interested in Computational Molecular Biology.


Pattern Discovery in Biomolecular Data

Pattern Discovery in Biomolecular Data
Author: Jason T. L. Wang
Publisher: Oxford University Press
Total Pages: 272
Release: 1999-10-28
Genre: Science
ISBN: 0190283726

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Finding patterns in biomolecular data, particularly in DNA and RNA, is at the center of modern biological research. These data are complex and growing rapidly, so the search for patterns requires increasingly sophisticated computer methods. Pattern Discovery in Biomolecular Data provides a clear, up-to-date summary of the principal techniques. Each chapter is self-contained, and the techniques are drawn from many fields, including graph theory, information theory, statistics, genetic algorithms, computer visualization, and vision. Since pattern searches often benefit from multiple approaches, the book presents methods in their purest form so that readers can best choose the method or combination that fits their needs. The chapters focus on finding patterns in DNA, RNA, and protein sequences, finding patterns in 2D and 3D structures, and choosing system components. This volume will be invaluable for all workers in genomics and genetic analysis, and others whose research requires biocomputing.


Molecular Data Analysis Using R

Molecular Data Analysis Using R
Author: Csaba Ortutay
Publisher: John Wiley & Sons
Total Pages: 354
Release: 2017-02-06
Genre: Medical
ISBN: 1119165024

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This book addresses the difficulties experienced by wet lab researchers with the statistical analysis of molecular biology related data. The authors explain how to use R and Bioconductor for the analysis of experimental data in the field of molecular biology. The content is based upon two university courses for bioinformatics and experimental biology students (Biological Data Analysis with R and High-throughput Data Analysis with R). The material is divided into chapters based upon the experimental methods used in the laboratories. Key features include: • Broad appeal--the authors target their material to researchers in several levels, ensuring that the basics are always covered. • First book to explain how to use R and Bioconductor for the analysis of several types of experimental data in the field of molecular biology. • Focuses on R and Bioconductor, which are widely used for data analysis. One great benefit of R and Bioconductor is that there is a vast user community and very active discussion in place, in addition to the practice of sharing codes. Further, R is the platform for implementing new analysis approaches, therefore novel methods are available early for R users.