Biochemical Biomarkers And Neurodegenerative Diseases PDF Download
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Author | : Manuel Menéndez-González |
Publisher | : Frontiers Media SA |
Total Pages | : 123 |
Release | : 2014-12-03 |
Genre | : Biochemical markers |
ISBN | : 2889194000 |
Download Clinical use of biomarkers for neurodegenerative disorders Book in PDF, ePub and Kindle
The prevalence of neurodegenerative disorders is increasing dramatically and one of the major challenges today is the need of early and accurate diagnosis, the other is the need of more effective therapies -in turn the development of such therapies also requires early and accurate diagnosis-. The main hope for an earlier and more accurate diagnosis comes from the use of biomarkers. Much research is being done trying to solve the many interrogates related to the role of biomarkers in clinical practice, including the early diagnosis, differential diagnosis and follow-up of neurodegenerative disorders. This is a field where translational research is intense enough to make this topic interesting for basic researchers and clinicians. Indeed, the amount and quality of articles received in response to the call for contributions was very good. This eBook contains a good amount of high quality articles devoted to diverse techniques across several neurodegenerative disorders from different perspectives, including original reports, reviews, methods reports and opinion letters on biochemical biomarkers in biological fluids, neuroimaging techniques and multidimensional approaches linking clinical findings with biomarkers. The disorders covered are also diverse: Alzheimer’s disease, Frontotemporal Dementia, Dementia with Lewy Bodies, Huntington’s disease, Parkinson’s disease among others. As we can learn from articles in this Research Topic, biomarkers are allowing us to expand the knowledge on the biological and anatomical basis of neurodegenerative diseases and to implement diagnostic techniques in clinical practice and clinical trials.
Author | : Daniela Galimberti |
Publisher | : Springer Science & Business |
Total Pages | : 266 |
Release | : 2014-04-23 |
Genre | : Medical |
ISBN | : 144716380X |
Download Neurodegenerative Diseases Book in PDF, ePub and Kindle
This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic research into biomarkers for early diagnosis. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.
Author | : Kevin K. W. Wang |
Publisher | : CRC Press |
Total Pages | : 647 |
Release | : 2014-10-28 |
Genre | : Medical |
ISBN | : 1482239833 |
Download Biomarkers of Brain Injury and Neurological Disorders Book in PDF, ePub and Kindle
This book explores the recent advances in the techniques and platforms used in biomarker research that have revolutionized the way we study, diagnose, and treat brain injury conditions. The contributors describe different biomarker studies pertaining to brain injury and other neurological disorders and analyze the different models and technologies
Author | : Marcello Ciaccio |
Publisher | : Mdpi AG |
Total Pages | : 156 |
Release | : 2021-11-04 |
Genre | : Science |
ISBN | : 9783036517223 |
Download Biochemical Biomarkers and Neurodegenerative Diseases Book in PDF, ePub and Kindle
In this book, we collected scientific articles, including reviews and research articles, showcasing the lastest literature on the importance of biochemical biomarkers in the management of neurodegenerative diseases, from screening to diagnosis, prognosis, and treatment.
Author | : Vishal S. Vaidya |
Publisher | : John Wiley & Sons |
Total Pages | : 646 |
Release | : 2010-10-05 |
Genre | : Science |
ISBN | : 0470452242 |
Download Biomarkers Book in PDF, ePub and Kindle
This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson’s, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process.
Author | : Elizabeth A. Thomas |
Publisher | : Springer Nature |
Total Pages | : 476 |
Release | : 2023-11-13 |
Genre | : Medical |
ISBN | : 3031328159 |
Download Biomarkers for Huntington's Disease Book in PDF, ePub and Kindle
Huntington’s disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing progression of disease; however, current treatments for HD are limited, with only two FDA-approved drugs available to manage chorea. Encouragingly, however, several disease-modifying treatment approaches are in the therapeutic pipeline, with more than 200 clinical studies, and many more preclinical studies, in the works. Robust and reliable biomarkers are needed to predict disease onset, monitor disease progression and assess treatment responses. More specifically, biomarkers to stratify patients for clinical trials and biomarkers to track drug efficacy will certainly lead to improved clinical trial design and success. This book represents the first book focused solely on biomarkers for HD and represents a distinct resource that will be informative, not only for clinicians and those involved in clinical trial design, but also for a wide range of neurodegenerative disease researchers. This edited volume is written by top leaders in the field, and takes a cross-disciplinary approach to cover a broad spectrum of biomarker types, in order to provide the latest advances in the development of biochemical, molecular, imaging and digital biomarkers that have been investigated for HD. With the ultimate goal of treating patients, the development of disease-associated biomarkers has never been more important.
Author | : Robert Perneczky |
Publisher | : Springer Nature |
Total Pages | : 345 |
Release | : 2024 |
Genre | : Alzheimer's disease |
ISBN | : 1071637746 |
Download Biomarkers for Alzheimer's Disease Drug Development Book in PDF, ePub and Kindle
Zusammenfassung: This fully updated volume provides an up-to-date and comprehensive overview of the current state of technologies helping to accelerate Alzheimer's disease drug development. Addressing the latest advances in preclinical and clinical research, including new insights into the molecular mechanisms and emerging therapeutic strategies, the book continues by exploring digital biomarkers and advanced neuroimaging analysis which will transform how clinical trials in the Alzheimer's disease field are performed. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed implementation advice that leads to greater success in the lab or clinic. Authoritative and practical, Biomarkers for Alzheimer's Disease Drug Development, Second Edition seeks to inspire and inform future efforts to develop effective treatments for this devastating disease
Author | : Lars Lannfelt |
Publisher | : |
Total Pages | : 289 |
Release | : 2016 |
Genre | : Biochemical markers |
ISBN | : 9781493935604 |
Download Immunotherapy and Biomarkers in Neurodegenerative Disorders Book in PDF, ePub and Kindle
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 128 |
Release | : 2008-01-08 |
Genre | : Medical |
ISBN | : 0309178282 |
Download Neuroscience Biomarkers and Biosignatures Book in PDF, ePub and Kindle
Biomarkers, or biological markers, are quantitative measurements that offer researchers and clinicians valuable insight into diagnosis, treatment and prognosis for many disorders and diseases. A major goal in neuroscience medical research is establishing biomarkers for disorders of the nervous system. Given the promising potential and necessity for neuroscience biomarkers, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened a public workshop and released the workshop summary entitled Neuroscience Biomarkers and Biosignatures: Converging Technologies, Emerging Partnerships. The workshop brought together experts from multiple areas to discuss the most promising and practical arenas in neuroscience in which biomarkers will have the greatest impact. The main objective of the workshop was to identify and discuss biomarker targets that are not currently being aggressively pursued but that could have the greatest near-term impact on the rate at which new treatments are brought forward for psychiatric and neurological disorders.
Author | : Namita Agrawal |
Publisher | : Springer Nature |
Total Pages | : 442 |
Release | : |
Genre | : |
ISBN | : 9819742889 |
Download Altered Metabolism: A Major Contributor of Comorbidities in Neurodegenerative Diseases Book in PDF, ePub and Kindle