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Aromaticity in Heterocyclic Compounds

Aromaticity in Heterocyclic Compounds
Author: Tadeusz Marek Krygowski
Publisher: Springer Science & Business Media
Total Pages: 355
Release: 2009-01-30
Genre: Science
ISBN: 3540683291

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Heterocyclic chemistry is the biggest branch of chemistry covering two-thirds of the chemical literature. Aromaticity in Heterocyclic Compounds covers hot topics of frontier research summarized by reputed scientists in the field.


Aromatic Heterocyclic Chemistry

Aromatic Heterocyclic Chemistry
Author: David T. Davies
Publisher:
Total Pages: 89
Release: 2011
Genre: Aromatic compounds
ISBN: 9780191848858

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Heterocyclic compounds are of prime importance to organic chemists working in the chemical industry, and heterocyclic chemistry is therefore a fundamental topic in undergraduate chemistry courses. The emphasis of this short text is on synthetic aspects, rather than properties, and it covers the essential details and basic principles with reference to all the important classes of heterocyclic compounds. Instructional problems are included as an aid to comprehension, and references to more detailed texts are provided.


Fundamentals of Heterocyclic Chemistry

Fundamentals of Heterocyclic Chemistry
Author: Louis D. Quin
Publisher: John Wiley & Sons
Total Pages: 344
Release: 2010-07-08
Genre: Science
ISBN: 9780470626535

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Heterocyclic chemistry is of prime importance as a sub-discipline of Organic Chemistry, as millions of heterocyclic compounds are known with more being synthesized regularly Introduces students to heterocyclic chemistry and synthesis with practical examples of applied methodology Emphasizes natural product and pharmaceutical applications Provides graduate students and researchers in the pharmaceutical and related sciences with a background in the field Includes problem sets with several chapters


Structure, Bonding and Reactivity of Heterocyclic Compounds

Structure, Bonding and Reactivity of Heterocyclic Compounds
Author: Frank De Proft
Publisher: Springer
Total Pages: 199
Release: 2014-11-03
Genre: Science
ISBN: 3642451497

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The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.


The Principles of Heterocyclic Chemistry

The Principles of Heterocyclic Chemistry
Author: Alan R. Katritzky
Publisher: Elsevier
Total Pages: 199
Release: 2013-10-22
Genre: Science
ISBN: 1483274519

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The Principles of Heterocyclic Chemistry presents a unified account of fundamental heterocyclic chemistry with the emphasis placed on the correlations between the methods of preparation and the properties of the various ring systems. This book opens with an introductory chapter that discusses fundamental concepts of the electronic theory of organic chemistry and the relationship of heterocyclic and carbocyclic aromatic compounds. This is followed by separate chapters on the chemistry of the six-membered ring compounds containing one or more heteroatoms, five-membered ring compounds, three- and four-membered rings, and the physical properties of representative heterocyclic compounds. Each chapter begins with introductory section that surveys the various ring types, gives the systems of nomenclature and numbering, and mentions a few important natural and synthetic compounds. Syntheses starting from aliphatic and carbocyclic compounds are then given. The preparation of one heterocyclic compound from another is considered as a reaction of the starting material. The reactions of aromatic and non-aromatic compounds are discussed separately. This book contains the essential heterocyclic chemistry required by an Undergraduate or Graduate student for his course-work, and it is hoped that it will be found stimulating by many a more senior teacher and researcher.


Introduction to Heterocyclic Chemistry

Introduction to Heterocyclic Chemistry
Author: Peter A. Jacobi
Publisher: John Wiley & Sons
Total Pages: 272
Release: 2018-08-08
Genre: Science
ISBN: 1119417686

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A unique approach to a core topic in organic chemistry presented by an experienced teacher to students and professionals Heterocyclic rings are present in the majority of known natural products, contributing to enormous structural diversity. In addition, they often possess significant biological activity. Medicinal chemists have embraced this last property in designing most of the small molecule drugs in use today. This book offers readers a fundamental understanding of the basics of heterocyclic chemistry and their occurrence in natural products such as amino acids, DNA, vitamins, and antibiotics. Based on class lectures that the author has developed over more than 40 years of teaching, it focuses on the chemistry of such heterocyclic substances and how they differ from carbocyclic systems. Introductory Heterocyclic Chemistry offers in-depth chapters covering naturally occurring heterocycles; properties of aromatic heterocycles; π-deficient heterocycles; π-excessive heterocycles; and ring transformations of heterocycles. It then offers an overview of 1,3-dipolar cycloadditions before finishing up with a back-to-basics section on nitriles and amidines. Presents a conversational approach to a fundamental topic in organic chemistry teaching Offers a unique look at this core organic chemistry topic via important naturally occurring and/or biologically active heterocycles Based on the author's many years of class lectures for teaching at the undergraduate and graduate level as well as pharmaceutical-industry courses Clear, concise, and accessible for advanced students of chemistry to gain a fundamental understanding of the basics of heterocyclic chemistry Introductory Heterocyclic Chemistry is an excellent text for undergraduate and graduate students as well as chemists in industrial environments in chemistry, pharmacy, medicinal chemistry, and biology.


Fundamental Aliphatic Chemistry

Fundamental Aliphatic Chemistry
Author: P. W. G. Smith
Publisher: Elsevier
Total Pages: 238
Release: 2014-04-24
Genre: Science
ISBN: 1483139069

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Organic Chemistry for General Degree Students is written to meet the requirements of the London General Internal examination and degree examinations of a similar standing. It will also provide for the needs of students taking the Part 1 examination for Graduate Membership of the Royal Institute of Chemistry, or the Higher National Certificate, whilst the treatment is such that Ordinary National Certificate courses can be based on the first two volumes Within the limits broadly defined by the syllabus, the aim of this first volume is to provide a concise summary of the important general methods of preparation and properties of the main classes of aliphatic compounds. Due attention is paid to practical considerations with particular reference to important industrial processes. At the same time, the fundamental theoretical principles of organic chemistry are illustrated by the discussion of a selection of the more important reaction mechanisms. Questions and problems are included, designed to test the student’s appreciation of the subject and his ability to apply the principles embodied therein. A selection of questions set in the relevant examinations is also included.


Aromaticity

Aromaticity
Author: Israel Fernandez
Publisher: Elsevier
Total Pages: 517
Release: 2021-05-16
Genre: Science
ISBN: 0128227435

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Evaluating the aromaticity of a molecular system and the influence of this concept on its properties is a crucial step in the development of novel aromatic systems. Modern computational methods can provide researchers with a high level of insight into such aromaticity, but identifying the most appropriate method for assessing a specific system can prove difficult. Aromaticity: Modern Computational Methods and Applications reviews the latest state-of-the-art computational methods in this field and discusses their applicability for evaluating the aromaticity of a system. In addition to covering aromaticity for typical organic molecules, this volume also explores systems possessing transition metals in their structures, macrocycles and even transition structures. The influence of the aromaticity on the properties of these species (including the structure, magnetic properties and reactivity) is highlighted, along with potential applications in fields including materials science and medicinal chemistry. Finally, the controversial and fuzzy nature of aromaticity as a concept is discussed, providing the basis for an updated and more comprehensive definition of this concept. Drawing on the knowledge of an international team of experts, Aromaticity: Modern Computational Methods and Applications is a unique guide for anyone researching, studying or applying principles of aromaticity in their work, from computational and organic chemists to pharmaceutical and materials scientists. Reviews a range of computational methods to assess the aromatic nature of different compounds, helping readers select the most useful tool for the system they are studying Presents a complete guide to the key concepts and fundamental principles of aromaticity Provides guidance on identifying which variables should be modified to tune the properties of an aromatic system for different potential applications


Organic Chemistry, Volume Two

Organic Chemistry, Volume Two
Author: Frank C. Whitmore
Publisher: Courier Dover Publications
Total Pages: 418
Release: 2011-12-14
Genre: Science
ISBN: 0486607011

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This volume discusses the properties of aromatic compounds, alkaloids and other types of heterocyclic compounds, organophosphorus, and organometallic compounds.


Aromatic Chemistry

Aromatic Chemistry
Author: Malcolm Sainsbury
Publisher:
Total Pages: 99
Release: 1992-08-27
Genre: Science
ISBN: 0198556748

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All the basic principles of this important topic are clearly presented here in an account which takes as examples many compounds of industrial and biological significance. Consideration is given to the structure, reactions, and properties of benzene and classes of aromatic compounds derived from it, and topics such as thermodynamic versus kinetic control and pericyclic reactions are introduced. The text also covers polycyclic arenes and the small and large ring systems which are embraced by the wider definition of aromaticity.