Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Application Of Newer Organometallic Reagents To The Total Synthesis Of Natural Products PDF full book. Access full book title Application Of Newer Organometallic Reagents To The Total Synthesis Of Natural Products.
| Author | : Martin Semmelhack |
| Publisher | : |
| Total Pages | : 14 |
| Release | : 1985 |
| Genre | : |
| ISBN | : |
| Author | : Paul H. Stenson |
| Publisher | : |
| Total Pages | : 234 |
| Release | : 1986 |
| Genre | : |
| ISBN | : |
| Author | : Pei-Qiang Huang |
| Publisher | : John Wiley & Sons |
| Total Pages | : 512 |
| Release | : 2018-10-16 |
| Genre | : Science |
| ISBN | : 1118605403 |
Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals
| Author | : Herbert Andrew Kirst |
| Publisher | : |
| Total Pages | : |
| Release | : 1972 |
| Genre | : |
| ISBN | : |
| Author | : Bruce H. Lipshutz |
| Publisher | : John Wiley & Sons |
| Total Pages | : 528 |
| Release | : 2013-12-02 |
| Genre | : Science |
| ISBN | : 1118651448 |
Provides detailed procedures and useful hints on organometallic reactions of Cu, Rh, Ni, and Au With contributions from leading organic chemists who specialize in the use of organometallics in organic synthesis, this acclaimed Manual offers an especially valuable resource for all synthetic chemists, providing a practical reference for conducting transition metal mediated synthetic reactions. This Fourth Manual is divided into four chapters: Chapter I: Organocopper Chemistry Chapter II: Organorhodium Chemistry Chapter III: Organonickel Chemistry Chapter IV: Organogold Chemistry Each of these newly written chapters features detailed, practical examples from the literature that guide readers through the preparation of organometallic reagents and their applications in organic synthesis. Procedures are presented in the Manual's acclaimed step-by-step recipe format, enabling both novices and experienced synthetic chemists to perform all the reactions with ease. In addition, the Manual features: Extensive background information on the organometallic chemistry of Cu, Rh, Ni, and Au References to the primary literature facilitating further investigation of all the reactions covered in the Manual Mechanistic considerations to help readers better understand how the desired products are formed Future research opportunities for each organometallic class Organometallics in Synthesis provides extensive and detailed information enabling synthetic chemists to readily assess the applicability of a synthetic method to a given need, and then to perform the reaction with confidence. The Manual covers both established organometallic procedures along with the most recently published protocols. Industrial processes are increasingly relying on organometallic chemistry. In this Manual, readers will find applications to such fields as natural products total synthesis, pharmaceuticals, fine chemicals, biotechnology, agricultural science, polymers, and materials science.
| Author | : Jie Jack Li |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 292 |
| Release | : 2013-03-14 |
| Genre | : Science |
| ISBN | : 3642340652 |
'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.
| Author | : Keiji Maruoka |
| Publisher | : |
| Total Pages | : 252 |
| Release | : 1980 |
| Genre | : Chemical tests and reagents |
| ISBN | : |
| Author | : |
| Publisher | : |
| Total Pages | : 139 |
| Release | : 2006 |
| Genre | : |
| ISBN | : |
This dissertation summarizes the development of novel synthetic methods involving organometallic reagents and their application in the total synthesis of the natural product eupomatilone 2. These newly discovered reactions including the palladium-catalyzed cross-coupling of allyl acetates with organosiloxanes and the diastereoselective synthesis of cis- and trans-a-methylene-y-lactones utilizing Baylis-Hillman adducts as precursors. Another important aspect of the research is the application of some of the methods in total synthesis of eupomtilone 2. The new synthetic methodologies involving organometallic reagesnts developed in this dissertation are important transformations in modern organic synthesis. Mild reaction conditions, tolerance of various organic functional groups, and high selectivity are advantages of these methodologies. The ability to recycle the catalytic system in some cases is another attractive feature for PEG-involved methods. The short and efficient strategy for the synthesis fo eupomatilone 2 could serve as a catalyst for research in this area.
| Author | : Dietmar Seyferth |
| Publisher | : |
| Total Pages | : 510 |
| Release | : 1976 |
| Genre | : Chemical tests and reagents |
| ISBN | : |
| Author | : Manfred Schlosser |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1008 |
| Release | : 2013-05-28 |
| Genre | : Science |
| ISBN | : 1118484754 |
WINNER of the 2013 PROSE Award in Chemistry & Physics This latest edition enables readers to master new classes of organometallic compounds and syntheses A popular resource used by synthetic organic chemists around the world, this book enables readers to conduct seamless synthetic reactions involving key organometallics. Each reaction is set forth in the book's acclaimed recipe-style format so that readers can easily replicate the results in their own labs. Moreover, each chapter has been written by a world leader in the field of organometallics in organic synthesis. These authors offer hands-on guidance and practical examples illustrating the preparation of organometallics and its application in organic synthesis. This Third Manual of Organometallics in Synthesis features completely new content and topics, with an eye towards providing researchers with the most useful and practical reference on the synthesis of organometallics. Organized into chapters by type of organometallic compound, the book covers: Organoalkali chemistry Organomagnesium and organozinc chemistry Organosilicon and relating organotin chemistry Organoiron chemistry Organopalladium chemistry Within each chapter, readers will find background information to learn more about the class of organometallics as well as mechanistic considerations. The authors thoroughly discuss the various methods of preparing the organometallic compounds presented in the book and outline their uses in synthetic reactions. In addition to current applications, the authors explore future research opportunities for each organometallic class. References at the end of each chapter enable readers to explore all the topics in greater depth. More and more industrial processes rely on organometallic chemistry. As a result, readers will find this book's step-by-step instructions essential in such fields as natural product synthesis, pharmaceuticals, fine chemicals, biotechnology, polymers, and materials science.
