Aging Experiments PDF Download
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| Author | : Trygve O. Tollefsbol |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 462 |
| Release | : 2009-11-11 |
| Genre | : Medical |
| ISBN | : 1441906398 |
Download Epigenetics of Aging Book in PDF, ePub and Kindle
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 280 |
| Release | : 2006-02-13 |
| Genre | : Social Science |
| ISBN | : 0309164915 |
Download When I'm 64 Book in PDF, ePub and Kindle
By 2030 there will be about 70 million people in the United States who are older than 64. Approximately 26 percent of these will be racial and ethnic minorities. Overall, the older population will be more diverse and better educated than their earlier cohorts. The range of late-life outcomes is very dramatic with old age being a significantly different experience for financially secure and well-educated people than for poor and uneducated people. The early mission of behavioral science research focused on identifying problems of older adults, such as isolation, caregiving, and dementia. Today, the field of gerontology is more interdisciplinary. When I'm 64 examines how individual and social behavior play a role in understanding diverse outcomes in old age. It also explores the implications of an aging workforce on the economy. The book recommends that the National Institute on Aging focus its research support in social, personality, and life-span psychology in four areas: motivation and behavioral change; socioemotional influences on decision-making; the influence of social engagement on cognition; and the effects of stereotypes on self and others. When I'm 64 is a useful resource for policymakers, researchers and medical professionals.
| Author | : Gavin J. Andrews |
| Publisher | : Routledge |
| Total Pages | : 341 |
| Release | : 2004-11-10 |
| Genre | : Science |
| ISBN | : 1134361378 |
Download Ageing and Place Book in PDF, ePub and Kindle
During recent years, an increasing amount of academic research has focused on older people with a particular emphasis on settings, places and spaces. This book provides a comprehensive review of research and the policy area of 'ageing and place'. An insightful book on an important topic, Andrews and Phillips have together edited a valuable information and reference source for those with interests in the spatial dimensions of ageing in the twenty-first century. Ranging from macro-scale perspectives on the distribution of older populations on national scales, to the meaning of specific local places and settings to older individuals, on the micro-scale, the book spans an entire range of research traditions and international perspectives.
| Author | : João Paulo Guimarães |
| Publisher | : transcript Verlag |
| Total Pages | : 227 |
| Release | : 2023-08-31 |
| Genre | : Social Science |
| ISBN | : 3839462835 |
Download Aging Experiments Book in PDF, ePub and Kindle
The sustained expansion of the life span and the attendant demographic changes in the West have fuelled the production of cultural texts that explore alternative representations of aging and old age. The contributors to this volume show how artists in science-fiction, fantasy and the avant-garde develop visions of late life transformation, improvisation and adaptation to new circumstances. The studies particularly focus on perspectives on aging that challenge the predominant narratives of decline as well as fantasies of eternal youth, as defined by neoliberal notions of health, able-bodiedness, agency, self-improvement, progress, plasticity and productivity.
| Author | : |
| Publisher | : |
| Total Pages | : 36 |
| Release | : 1961 |
| Genre | : Aging |
| ISBN | : |
Download Research Programs in Aging Book in PDF, ePub and Kindle
| Author | : Experimental Aging Research |
| Publisher | : |
| Total Pages | : 84 |
| Release | : 1977 |
| Genre | : |
| ISBN | : |
Download Experimental Aging Research Book in PDF, ePub and Kindle
| Author | : National Institutes of Health (U.S.). Center for Aging Research |
| Publisher | : |
| Total Pages | : 104 |
| Release | : 1962 |
| Genre | : Age and employment |
| ISBN | : |
Download Research Programs in Aging Book in PDF, ePub and Kindle
| Author | : Michael R. Rose |
| Publisher | : Oxford University Press |
| Total Pages | : 189 |
| Release | : 2005-09-15 |
| Genre | : Science |
| ISBN | : 0198039867 |
Download The Long Tomorrow Book in PDF, ePub and Kindle
The conquest of aging is now within our grasp. It hasn't arrived yet, writes Michael R. Rose, but a scientific juggernaut has started rolling and is picking up speed. A long tomorrow is coming. In The Long Tomorrow, Rose offers us a delightfully written account of the modern science of aging, spiced with intriguing stories of his own career and leavened with the author's engaging sense of humor and rare ability to make contemporary research understandable to nonscientists. The book ranges from Rose's first experiments while a graduate student--counting a million fruit fly eggs, which took 3,000 hours over the course of a year--to some of his key scientific discoveries. We see how some of his earliest experiments helped demonstrate that "the force of natural selection" was key to understanding the aging process--a major breakthrough. Rose describes how he created the well-known Methuselah Flies, fruit flies that live far longer than average. Equally important, Rose surveys the entire field, offering colorful portraits of many leading scientists and shedding light on research findings from around the world. We learn that rodents given fifteen to forty percent fewer calories live about that much longer, and that volunteers in Biosphere II, who lived on reduced caloric intake for two years, all had improved vital signs. Perhaps most interesting, we discover that aging hits a plateau and stops. Popular accounts of Rose's work have appeared in The New Yorker, Time magazine, and Scientific American, but The Long Tomorrow is the first full account of this exciting new science written for the general reader. "Among his peers, Rose is considered a brilliantly innovative scientist, who has almost single-handedly brought the evolutionary theory of aging from an abstract notion to one of the most exciting topics in science."--Malcolm Gladwell, The New Yorker
| Author | : Ellen J. Langer |
| Publisher | : Random House Digital, Inc. |
| Total Pages | : 239 |
| Release | : 2009 |
| Genre | : Psychology |
| ISBN | : 0345502043 |
Download Counterclockwise Book in PDF, ePub and Kindle
Scientifically riveting and practically empowering, "Counterclockwise" offers a bold new way to think about aging and lifelong health from the trailblazing social psychologist and author of the bestselling classic "Mindfulness."
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 367 |
| Release | : 2016-11-08 |
| Genre | : Medical |
| ISBN | : 0309448093 |
Download Families Caring for an Aging America Book in PDF, ePub and Kindle
Family caregiving affects millions of Americans every day, in all walks of life. At least 17.7 million individuals in the United States are caregivers of an older adult with a health or functional limitation. The nation's family caregivers provide the lion's share of long-term care for our older adult population. They are also central to older adults' access to and receipt of health care and community-based social services. Yet the need to recognize and support caregivers is among the least appreciated challenges facing the aging U.S. population. Families Caring for an Aging America examines the prevalence and nature of family caregiving of older adults and the available evidence on the effectiveness of programs, supports, and other interventions designed to support family caregivers. This report also assesses and recommends policies to address the needs of family caregivers and to minimize the barriers that they encounter in trying to meet the needs of older adults.
