Advances In Targeted Cancer Therapy PDF Download
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Author | : Iago Dillion Lima Cavalcanti |
Publisher | : Springer Nature |
Total Pages | : 109 |
Release | : 2021-02-24 |
Genre | : Medical |
ISBN | : 3030683346 |
Download Advances in Cancer Treatment Book in PDF, ePub and Kindle
This work covers the pathophysiology of cancer, exploring the difficulty of optimal treatment due to the complexity and diversity of cancer types. The search for distinctive molecular biology characteristics of tumor cells is especially relevant in the identification of overexpressed receptors and proteins that can be used as a target for cancer treatment. We highlight the main therapeutic modalities, particularly conventional systemic chemotherapy, addressing its mechanisms of action, therapeutic classes and even the toxic effects. We also describe the main tumor markers, their importance in the diagnosis and treatment of cancer, and the specificity of tumor cells. The first chapters serve as an introduction to the central topic of this book, targeted therapy. Key aspects of target therapy, such as classes of drugs, immunotherapy, monoclonal antibodies, checkpoint inhibitors, cancer vaccines and tyrosine kinase inhibitors are presented, and, for each one, the benefits, as well as the adverse effects are reported. Chapter 6 compares conventional systemic chemotherapy and targeted therapy, identifies the risks and benefits and also the eligibility criteria for patient care. The possibility of targeted therapy replacing conventional chemotherapy is discussed while reviewing studies that demonstrate the benefits of combining both types of treatment. Finally, the introduction of pharmaceutical nanotechnology to improve antineoplastic agents is addressed in the last chapter and sets the direction for future research in cancer treatment. This is a valuable resource for many health professionals including physicians, pharmacists, nurses, researchers and students interested in the field of oncology.
Author | : Richard M. Schultz |
Publisher | : Springer Science & Business Media |
Total Pages | : 294 |
Release | : 2006-01-24 |
Genre | : Medical |
ISBN | : 3764374144 |
Download Advances in Targeted Cancer Therapy Book in PDF, ePub and Kindle
There have been tremendous advances in our understanding of molecular and tumor biology during the past few years. In the field of cancer therapeutics, it is expected that cytotoxic drug approaches will be gradually replaced with treatments based on biological targeted approaches. Hopefully these new targeted therapies will significantly increase efficacy and lack the devastating and troublesome side effects elicited by cytotoxic chemotherapy. This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and antibody-based therapeutics. The emphasis is on preclinical development, including target validation, development of biomarkers, strategies for combination approaches, and development of resistance. The particular challenges involved in translating these data to clinical application are discussed. This volume should be of broad general interest to researchers and clinicians involved in cancer therapy as well as other scientists interested in current strategies for cancer treatment.
Author | : Rui-hua Xu |
Publisher | : |
Total Pages | : |
Release | : 2016 |
Genre | : |
ISBN | : 9781618962744 |
Download Advances in Targeted Cancer Therapy Book in PDF, ePub and Kindle
Author | : Gw Sledge |
Publisher | : Clinical Pub |
Total Pages | : 0 |
Release | : 2012-06 |
Genre | : Breast |
ISBN | : 9781846920660 |
Download Targeted Therapies in Breast Cancer Book in PDF, ePub and Kindle
This new volume updates the reader on selected areas of targeted therapy in breast cancer, with special emphasis on chemoprevention strategies, drug resistance, biomarkers, combination chemotherapy, angiogenesis inhibition and pharmacogenomics in the context of clinical efficacy. This selected review of targeted therapies will guide the reader on effective treatment as part of an integrated programme of patient management.
Author | : Xin-Yuan Liu |
Publisher | : Elsevier |
Total Pages | : 701 |
Release | : 2012-05-18 |
Genre | : Medical |
ISBN | : 012397836X |
Download Recent Advances in Cancer Research and Therapy Book in PDF, ePub and Kindle
Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.
Author | : S. Peters |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 126 |
Release | : 2014-02-19 |
Genre | : Medical |
ISBN | : 3318025429 |
Download Successes and Limitations of Targeted Cancer Therapy Book in PDF, ePub and Kindle
The treatment of patients with advanced malignancies has undergone remarkable change in the last few years. While in the past decisions about systemic therapy were largely based on the performance status of a patient, oncologists today also take into account the pathological and molecular characteristics of the patient’s tumor. Targeting specific molecular pathways important for tumorigenesis has become the preferred way of treatment for many types of malignancies. With these advances come new challenges including the optimization of therapy, recognizing and dealing with side effects and, importantly, the development of resistance. This book provides an up-to-date overview of the advances and limitations of targeted therapy for several tumor entities including breast cancer, colon cancer, gastrointestinal stromal tumors, lung cancer, melanoma, ovarian cancer and renal cell carcinoma. Written by over a dozen internationally renowned scientists, the book is suitable for advanced students, postdoctoral researchers, scientists and clinicians who wish to update their knowledge of the latest approaches to targeted cancer therapies.
Author | : Manfred Dietel |
Publisher | : Springer |
Total Pages | : 0 |
Release | : 2014-11-23 |
Genre | : Medical |
ISBN | : 9783642432439 |
Download Targeted Therapies in Cancer Book in PDF, ePub and Kindle
From its introduction, oncological chemotherapy has been encumbered by poor selectivity because antiproliferative drugs are often toxic not only to tumor cells but also to important populations of the body’s non-neoplastic cells. Modern targeted therapies interact with defined molecules present on cancer cells, adding increased selectivity to their toxic effects. This book presents an integrated critical view on the theories, mechanisms, problems and pitfalls of the targeted therapy approach.
Author | : Razelle Kurzrock |
Publisher | : Springer Science & Business Media |
Total Pages | : 447 |
Release | : 2008-03-07 |
Genre | : Medical |
ISBN | : 1603274243 |
Download Targeted Cancer Therapy Book in PDF, ePub and Kindle
Emerging technologies in target identification, drug discovery, molecular markers, and imaging are rapidly changing the face of cancer. This book provides a foundation of knowledge in targeted cancer therapeutics. The treatment of cancer is increasingly being individualized, based on an understanding of underlying biologic mechanisms. Poised to change the landscape in oncology, this volume provides a state-of-the-art overview. It will be valuable to practicing and academic physicians, fellows, residents and students, as well as basic scientists, interested in the cancer field.
Author | : Tod W. Speer |
Publisher | : Lippincott Williams & Wilkins |
Total Pages | : 564 |
Release | : 2012-03-28 |
Genre | : Medical |
ISBN | : 1451153260 |
Download Targeted Radionuclide Therapy Book in PDF, ePub and Kindle
Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.
Author | : Daniel D. Karp |
Publisher | : Lippincott Williams & Wilkins |
Total Pages | : 310 |
Release | : 2014-09-09 |
Genre | : Medical |
ISBN | : 1469894580 |
Download Handbook of Targeted Cancer Therapy Book in PDF, ePub and Kindle
Make optimal use of the latest personalized therapeutic strategies with Handbook of Targeted Cancer Therapy! This concise, practical oncology reference examines more than 140 targeted therapy agents for which clinical trial data are available, and explains when and how you can use them to most effectively combat cancer. Approach clinical challenges from any direction with separate sections on Targets by Organ Site, Carcinogenesis from the Perspective of Targeted Therapy, Molecular Targets and Pathways, and Targeted Therapy Agents. Find information easily thanks to a color-coded format and an intuitive organization. Access the complete contents online and on mobile devices, with regular updates to include newly approved treatments. Important state of the art cancer information for caregivers, researchers, other health care professionals, and even patients