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A Carrier at Risk

A Carrier at Risk
Author: Mariano Sciaroni
Publisher: Latin America@War
Total Pages: 0
Release: 2019
Genre: Falkland Islands War, 1982
ISBN: 9781911628705

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The naval warfare of the last few decades appears dominated by operations of fast missile craft and a wide diversity of other minor vessels in so-called 'littoral warfare'. As so often, the reality is entirely different. Submarine and anti-submarine warfare remain one of most sophisticated forms of armed conflicts to this day. Unsurprisingly, consi


Assessing Genetic Risks

Assessing Genetic Risks
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 353
Release: 1994-01-01
Genre: Medical
ISBN: 0309047986

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Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.


Beat the Heart Attack Gene

Beat the Heart Attack Gene
Author: Bradley Bale
Publisher: Turner Publishing Company
Total Pages: 232
Release: 2014-02-04
Genre: Health & Fitness
ISBN: 1630260568

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A revolutionary, personalized guide to preventing heart disease—America’s #1 killer Heart disease is the #1 cause of death in America. It affects 81 million Americans and is the culprit in one of every two deaths in the United States. Most people think that they are not at risk of a heart attack if they control their cholesterol and blood pressure, but they aren’t aware of other major risk factors. The good news is that with the right information and strategies, heart attacks are preventable—even if heart disease runs in the family. In Beat the Heart Attack Gene, world-renowned cardiovascular specialists Bradley Bale, MD and Amy Doneen, ARNP, present a new model for understanding and preventing heart disease. They explain the three different genetic types of cholesterol profiles and tailor treatments for each type, using their cutting-edge Bale/Doneen Method, a comprehensive, evidence-based medical treatment plan that detects cardiovascular disease (CVD) at early stages and stabilizes it with individualized medical and lifestyle therapy. Beat the Heart Attack Gene includes easy quizzes and self-tests that show how to determine cholesterol genotype as well as advice for how to apply that knowledge through and individualized lifestyle advice. For heart attack and stroke survivors, the Bale/Doneen Method also helps prevent recurrences by identifying and treating what's triggering the patient's disease—a crucial step that many cardiologists neglect. With their proven method utilized by healthcare professionals worldwide, Bale and Doneen empower readers by alerting them to potential health threats, and then offer personalized strategies so they can live healthy, active lives without fear of heart attack or stroke. Specifically, Beat the Heart Attack Gene addresses: *The hidden cause of most heart attacks *Early prevention methods *The dangerous cholesterol most doctors don’t check *Major red flags for heart attack and stroke risk, including gum disease *The genes that increase cardiovascular risk as much as smoking *The best and worst supplements and foods for your heart *10 surprising ways to prevent heart attacks


The Risk of a Lifetime

The Risk of a Lifetime
Author: Rivka Weinberg
Publisher: Oxford University Press
Total Pages: 279
Release: 2016
Genre: Health & Fitness
ISBN: 0190243708

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This original, comprehensive theory of procreative ethics explains what kind of act procreation is and when we may permissibly engage in it. In order to ascertain when the procreative risk is permissible to impose, Weinberg proposes contractualist principles to fairly attend to the interests prospective parents have in procreating and the interests future people have in a life of human flourishing. The book presents a solution to the non-identity problem as well as dilemmas regarding our liberal principles of autonomy, consent, and equality, which may seem to be in tension with our procreative practices.


The Carriers

The Carriers
Author: Anne Skomorowsky
Publisher: Columbia University Press
Total Pages: 118
Release: 2022-05-03
Genre: Medical
ISBN: 0231552289

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A tiny mutation on the X chromosome can shape a family’s history. Passed down from a “carrier” parent to a child, fragile X syndrome is the most common inherited cause of intellectual disability and autism. Beyond that—and a rarity among genetic disorders—some fragile X carriers not only transmit the mutation but also experience related conditions themselves. In such cases, carriers can have tremors, infertility, and psychiatric disorders that complicate raising children with fragile X syndrome—and all too often, they suffer in silence. The Carriers investigates this common but still little-known genetic condition and its life-altering consequences. Anne Skomorowsky reveals how this disorder afflicts families across generations, telling the stories of the mothers and grandparents of fragile X patients and considering how genes interact with family dynamics. She interweaves the personal narratives and family histories of the people affected by fragile X disorders with clear and accessible explanations of the science behind them. Skomorowsky unpacks the latest research on the fragile X mutation and explores the history of its discovery. She highlights the roles of women as carriers, caregivers, and researchers who have made astonishing scientific breakthroughs over the last three decades. The Carriers is an essential book for fragile X families, including those just learning they are carriers, and for all readers interested in the complexities of heredity, the ethical dilemmas of genetic medicine, and the relationship between genes and personality.


Hereditary Hearing Loss and Its Syndromes

Hereditary Hearing Loss and Its Syndromes
Author: Helga V. Toriello
Publisher: Oxford University Press
Total Pages: 749
Release: 2013-06-20
Genre: Medical
ISBN: 0199313881

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This is the third edition of the foremost medical reference on hereditary hearing loss. Chapters on epidemiology, embryology, non-syndromic hearing loss, and syndromic forms of hearing loss have all been updated with particular attention to the vast amount of new information on molecular mechanisms, and chapters on clinical and molecular diagnosis and on genetic susceptibility to ototoxic factors have been added. As in previous editions, the syndromes are grouped by system (visual, metabolic, cardiologic, neurologic, musculoskeletal, endocrine, etc.), with each chapter written by a recognized expert in the field. Written for practicing clinicians, this volume is an excellent reference for physicians, audiologists, and other professionals working with individuals with hearing loss and their families, and can also serve as a text for clinical training programs and for researchers in the hearing sciences.


Molecular and Genetic Basis of Renal Disease

Molecular and Genetic Basis of Renal Disease
Author: David B. Mount
Publisher: Elsevier Health Sciences
Total Pages: 604
Release: 2008-01-01
Genre: Medical
ISBN: 1416002529

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This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron as well as the most common genetic and acquired renal diseases. A comprehensive clinical review of Medelian renal disease is also be included. Detailed review of the molecular anatomy and pathophysiology of the nephron that provides relevant basic science to consider when diagnosing and managing patients with these disorders.


Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology
Author: William B. Coleman
Publisher: Academic Press
Total Pages: 634
Release: 2019-11-23
Genre: Medical
ISBN: 0128132582

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Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology


"Go Find Him and Bring Me Back His Hat"

Author: Mariano Sciaroni
Publisher: Helion and Company
Total Pages: 238
Release: 2020-11-23
Genre: History
ISBN: 1915113423

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When the Task Force of the Royal Navy started its southbound voyage, as the second major act during the Falklands/Malvinas War of 1982, its commanders assessed the Argentine submarines as the biggest threat. Even if limited in total size and scope, this threat was so conditioning that the conclusion was that it had to be neutralized at the earliest possible moment in time, otherwise no victory would have been possible. The British believed that the Argentines would wait for them in the waters of the war zone with two modern and dangerous German-made Type-209 submarines, and a modified US-made submarine from the times of the Second World War. To their good luck, this threat was quickly reduced to two, because during the first naval combat of the conflict, the old ARA Santa Fe was knocked out and captured by the Royal Navy at South Georgia. Further anti-submarine operations followed on 1 May 1982, when ARA San Luis attacked Royal Navy warships, and, in turn, was counterattacked, resulting in scenes reminiscent of those from the movie Das Boot. Avoiding its pursuers, the boat distanced before re-attacking a few days later – when multiple factors conspired to prevent it from becoming successful. Despite systematic pursuit by warships and helicopters of the Royal Navy, the submarine eventually returned to its home port in one piece. Because the other Argentinean Type-209, ARA Salta, was non-operational, the withdrawal of the ARA San Luis also prompted the withdrawal of all the major units of the Argentine Navy into shallow waters off the coast of South America. Although the undersea battlefield was thus actually empty of Argentine submarines, elements of the Royal Navy’s task force continued detecting and tracking multiple sonar contacts over the following days and weeks. Indeed, they ultimately fired no fewer than 31 torpedoes, 49 depth-charges and 21 mortar salvoes at these. "Go Find Him and Bring Me Back His Hat" is the story of the crews of 22 warships, submarines, anti-submarine-warfare helicopters, and Nimrod submarine-hunter aircraft, their intensive and advanced training, and combat experiences – a richly illustrated story that has never been told before.


Reproductive Genetics

Reproductive Genetics
Author: Sean Kehoe
Publisher: RCOG
Total Pages: 245
Release: 2009-11
Genre: Medical
ISBN: 1906985162

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This book presents the findings of the RCOG Study Group findings on genetics underlying reproductive function.