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40 Years of Continuous Renal Replacement Therapy

40 Years of Continuous Renal Replacement Therapy
Author: R. Bellomo
Publisher: Karger Medical and Scientific Publishers
Total Pages: 174
Release: 2018-03-29
Genre: Medical
ISBN: 331806307X

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Continuous renal replacement therapies (CRRT) started off as an alternative to hemo- or peritoneal dialysis. Today's machines and techniques are the result of 4 decades of developments, studies, and practices which can be divided into 4 distinct stages: exploration and development; birth of a new specialty called critical care nephrology; design of specific new devices and machines; and interaction among various specialists to adapt extracorporeal therapies for multiple organ support and sepsis. This book features contributions from prominent CRRT experts from around the world. It is an important tool for educating a new generation of nephrologists and intensivists. At the same time, it provides the most advanced CRRT users with the latest technological information, the most updated clinical evidence, and the personal opinion of key leaders who contributed to the last 40 years of history in the field.


Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy
Author: John A. Kellum
Publisher: Oxford University Press
Total Pages: 329
Release: 2016
Genre: Medical
ISBN: 019022553X

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Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.


ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes

ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes
Author: J.A. Kellum
Publisher: Karger Medical and Scientific Publishers
Total Pages: 218
Release: 2013-05-14
Genre: Medical
ISBN: 3318024074

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Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This book contains the resolutions of the most recent ADQI conferences on biomarkers in AKI (Dublin) and on cardio-renal syndromes (Venice). The first part answers specific questions about new biomarkers and their use and utility in AKI: What are the most suitable candidate molecules and physiologic measures, how solid and evidence based is the discovery phase? How can we incorporate the new biomarkers in the AKI conceptual model describing the evolution from susceptibility to insult, decreased GFR and organ death? Even if we have a positive biomarker pattern and we can identify patients at risk or patients with early or even subclinical AKI, how is this information affecting our clinical behavior and practice? The second part is dedicated to the appraisal of the current knowledge about the pathophysiological mechanisms involved in different forms of CRS: it contains contributions on the state-of-the-art knowledge and practice of CRS, particularly focusing on the pathophysiology of the five subtypes. Acute and chronic mechanisms of damage are explored in depth, with particular attention to the primacy of organ involvement and the subsequent pathways of organ crosstalk.Presenting the most recent research in the field of biomarkers, AKI and CRS, this publication is an important educational tool for advanced investigators and clinical experts, but also for students and fellows.


Pediatric Continuous Renal Replacement Therapy

Pediatric Continuous Renal Replacement Therapy
Author: Farahnak Assadi
Publisher: Springer
Total Pages: 171
Release: 2015-12-16
Genre: Medical
ISBN: 3319262025

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This book provides a current understanding of Continuous Renal Replacement Therapies (CRRT) techniques with a focus on drug dosing in critically ill children receiving CRRT. Strategies include the role of therapeutic drug monitoring, effect of CRRT on drug pharmacokinetics, variations in the drugs properties, newer kidney injury biomarkers and simple and easy methods for estimating drug clearance. The conclusion of this book features case reports focused on the patients’ symptoms and laboratory data as they present in clinical practice and the type of CRRT modality needed to provide quality, safety, and cost-effectiveness of patient care. Pediatric Continuous Renal Replacement Therapy will expand the clinical knowledge and experience of practicing nephrologists and other professionals involved in the care of children suffering from Acute Kidney Injury (AKI) to improve and sustain their quality of life.


Aspects in Continuous Renal Replacement Therapy

Aspects in Continuous Renal Replacement Therapy
Author: Ayman Karkar
Publisher: BoD – Books on Demand
Total Pages: 124
Release: 2019-04-17
Genre: Medical
ISBN: 1789855853

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Continuous renal replacement therapy (CRRT) is a slow and smooth continuous extracorporeal blood purification process. It is usually implemented over 24 hours to several days with gentle removal of fluid overload and excess uremic toxins. CRRT, which is based on the physiological principles of diffusion, ultrafiltration, convection, and adsorption, can be performed as slow continuous ultrafiltration, continuous veno-venous hemofiltration, continuous veno-venous hemodiafiltration, and continuous veno-venous hemodialysis. Over many years, CRRT has been shown to be an effective dialysis therapy for hemodynamically unstable patients with acute kidney injury, brain injury, and/or multiorgan failure in intensive care units. Aspects in CRRT covers selected important topics with a practical approach to the management of different aspects of CRRT. All chapters have been updated and are well referenced, supported by well-illustrated figures and tables, and written by distinguished and experienced authors. Aspects in CRRT is considered as a guide to daily practice in intensive care units, and a reference for medical and nursing staff involved in taking care of critically ill patients with acute kidney injury, sepsis, and multiorgan failure.


Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy
Author: John A. Kellum
Publisher: Oxford University Press
Total Pages: 329
Release: 2016
Genre: Medical
ISBN: 019022553X

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Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.


Critical Care Nephrology E-Book

Critical Care Nephrology E-Book
Author: Claudio Ronco
Publisher: Elsevier Health Sciences
Total Pages: 1840
Release: 2017-12-14
Genre: Medical
ISBN: 0323511996

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Comprehensive and clinically relevant, the 3rd Edition of Critical Care Nephrology provides authoritative coverage of the latest advances in critical care procedures for patients with renal diseases or disorders. Using common guidelines and standardized approaches to critically ill patients, this multidisciplinary reference facilitates better communication among all physicians who care for critically ill patients suffering from kidney disease, electrolyte and metabolic imbalances, poisoning, severe sepsis, major organ dysfunction, and other pathological events. Offers detailed discussions of different forms of organ support, artificial organs, infections, acute illness occurring in chronic hemodialysis patients, and much more. Places a special emphasis on therapeutic interventions and treatment procedures for a hands on clinical reference tool. Presents information clearly, in a format designed for easy reference – from basic sciences to clinical syndromes to diagnostic tools. Covers special populations such as children, diabetic patients, and the elderly. An exceptional resource for nephrologists, intensivists, surgeons, or critical care physicians – anyone who treats critically ill renal patients. Shares a combined commitment to excellence lead by Drs. Claudio Ronco, Rinaldo Bellomo, John Kellum, and Zaccaria Ricci – unparalleled leaders in this field. Addresses key topics with expanded coverage of acute kidney injury, stress biomarkers, and sepsis, including the latest developments on mechanisms and management. Provides up-to-date information on extracorporeal therapies from new editor Dr. Zaccaria Ricci.


Critical Care Nephrology and Renal Replacement Therapy in Children

Critical Care Nephrology and Renal Replacement Therapy in Children
Author: Akash Deep
Publisher: Springer
Total Pages: 456
Release: 2018-08-17
Genre: Medical
ISBN: 3319902814

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This book represents an invaluable resource for professionals for the diagnosis and treatment of acute kidney injury (AKI) in children and how to select and deliver the appropriate form of renal replacement therapy (RRT). Experts from all over the globe have come together to share their wide experience in the field of Critical Care Nephrology in children. Paediatric critical care nephrology is a complex and highly specialised field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time to address all the topics in the field of critical care nephrology in children in a unique book which is the first of its kind. This book covers the basics as well as advances in the field of Critical Care Nephrology. Each chapter is dedicated to practical aspects of a particular topic elucidating various management decision points. Each chapter is also accompanied with algorithms, figures and protocols in tabulated format. Information on how to manage specific conditions are contextualized with relevant background anatomy, physiology and biochemistry and practical examples. At the end of the chapter, there are key learning points. Paediatricians, nephrologists and paediatric intensivists, as well as paediatric critical care and nephrology nurses in all countries will find this book an invaluable reference text.


Peritoneal Dialysis Today

Peritoneal Dialysis Today
Author: Claudio Ronco
Publisher: Karger Medical and Scientific Publishers
Total Pages: 337
Release: 2003-01-01
Genre: Medical
ISBN: 3805575815

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Peritoneal dialysis (PD) is an invaluable tool in the treatment of patients with end-stage renal disease, which does not preclude a renal transplant, but incurs lower costs than other treatment options and represents an alternative when the vascular access is not feasible. Moreover, PD can be integrated in the armamentarium of different therapies and constitutes an important option when logistical or organizational problems are present. The publication on hand gives an account of the most recent studies on PD outcome and adequacy, exploring how different fluids, schedules and techniques may help to determine the most tolerated and effective dialysis for each patient. Novel systems including continuous flow PD are probing new limits of efficiency and performance. Biocompatibility and adequate correction of anemia are also among the issues discussed in this book, giving the reader the opportunity to refresh or expand his knowledge in the field. This publication definitely deserves a place on the desk of those who are engaged in the day-by-day activity of PD.